Intra-ischemic hypothermia has been demonstrated to be protective against ischemic
neuronal injury. The present study examined the effect of moderate hypothermia on the …

As part of the stress response, the 72 kDa heat shock protein (hsp 72) is induced in neurons
after ischemic and traumatic brain injury (TBI). To examine the stress response after TBI with …

In this study we investigated the time course, cell-type and stress-specific expression of
hsp70 mRNA and Hsp70 protein in glial cells and neurons in the rat brain following heat …

In situ hybridization was used to estimate regional levels of heat shock protein-70 (HSP-70)
mRNA and c-fos mRNA in two related models of focal cerebral ischemia. In the first model …

Focal ischemia results in striking changes in gene expression. Induction of hsp72, a member
of the family of 70 kDa heat shock/stress proteins is a widely studied component of the …

The significance and physiological implications of the expression of the 72-kd heat-shock
protein in ischemic tissue are unknown. To enhance our understanding of the relation …

Transfection of neurones with an adenoviral vector (Ad) expressing high levels of hsp70i
was shown to protect primary hippocampal cultures from heat stress. To investigate one of …

In response to many metabolic disturbances and injuries including stroke,
neurodegenerative disease, epilepsy and trauma, the cell mounts a stress response with …

Many kinds of injuries induce 72 kDa heat-shock protein (HSP70) in the central nervous
system. We investigated the role of HSP70 in promoting the survival of rat hippocampal …

The heat shock proteins (hsps) are expressed in normal cells but their expression is
enhanced by a number of different stresses including heat and ischemia. They play …