Putative functional alleles of DYX1C1 are not associated with dyslexia susceptibility in a large sample of sibling pairs from the UK

TS Scerri, SE Fisher, C Francks, IL MacPhie… - Journal of Medical …, 2004 - jmg.bmj.com
METHODS Family ascertainment The sample of 264 nuclear families analysed in this study
consists of 173 families described in previous reports10 and an additional set of 91 families …

Evaluation of candidate genes for DYX1 and DYX2 in families with dyslexia

Z Brkanac, NH Chapman… - American Journal of …, 2007 - Wiley Online Library
Dyslexia is a common heterogeneous disorder with a significant genetic component.
Multiple studies have replicated the evidence for linkage between variously defined …

Genetics of dyslexia: the evolving landscape

J Schumacher, P Hoffmann, C Schmäl… - Journal of medical …, 2007 - jmg.bmj.com
Dyslexia is among the most common neurodevelopmental disorders, with a prevalence of 5–
12%. At the phenotypic level, various cognitive components that enable reading and …

Identification of candidate genes for dyslexia susceptibility on chromosome 18

TS Scerri, S Paracchini, A Morris, IL MacPhie, J Talcott… - PloS one, 2010 - journals.plos.org
Background Six independent studies have identified linkage to chromosome 18 for
developmental dyslexia or general reading ability. Until now, no candidate genes have been …

Linkage analyses of chromosomal region 18p11-q12 in dyslexia

J Schumacher, IR König, E Plume, P Propping… - Journal of neural …, 2006 - Springer
Dyslexia is characterized as a significant impairment in reading and spelling ability that
cannot be explained by low intelligence, low school attendance or deficits in sensory acuity …

Evidence for a susceptibility locus on chromosome 6q influencing phonological coding dyslexia

TL Petryshen, BJ Kaplan, M Fu Liu… - American journal of …, 2001 - Wiley Online Library
A linkage study of 96 dyslexia families containing at least two affected siblings (totaling 877
individuals) has found evidence for a dyslexia susceptibility gene on chromosome 6q11. 2 …

A dominant gene for developmental dyslexia on chromosome 3

J Nopola-Hemmi, B Myllyluoma, T Haltia… - Journal of medical …, 2001 - jmg.bmj.com
Developmental dyslexia is a neurofunctional disorder characterised by an unexpected
difficulty in learning to read and write despite adequate intelligence, motivation, and …

Further evidence for DYX1C1 as a susceptibility factor for dyslexia

F Dahdouh, H Anthoni, I Tapia-Páez… - Psychiatric …, 2009 - journals.lww.com
Objective Dyslexia-susceptibility-1-candidate-1 (DYX1C1) was the first gene associated with
dyslexia. Since the original report of 2003, eight replication attempts have been published …

Genetic linkage analysis with dyslexia: evidence for linkage of spelling disability to chromosome 15

MM Nöthen, G Schulte-Koerne, T Grimm… - European child & …, 1999 - Springer
Dyslexia (reading and spelling disability) is one of the most frequently diagnosed disorders
in childhood. Twin studies of dyslexia have indicated that deficits in spelling are substantially …

[PDF][PDF] A 77-kilobase region of chromosome 6p22. 2 is associated with dyslexia in families from the United Kingdom and from the United States

C Francks, S Paracchini, SD Smith… - The American Journal of …, 2004 - cell.com
Several quantitative trait loci (QTLs) that influence developmental dyslexia (reading
disability [RD]) have been mapped to chromosome regions by linkage analysis. The most …