Inflammation, infection and venous thromboembolism
ME Colling, BE Tourdot, Y Kanthi - Circulation research, 2021 - Am Heart Assoc
The association between inflammation, infection, and venous thrombosis has long been
recognized; yet, only in the last decades have we begun to understand the mechanisms …
recognized; yet, only in the last decades have we begun to understand the mechanisms …
The emerging role of NETs in venous thrombosis and immunothrombosis
Venous thrombosis (VT), a leading cause of morbidity and mortality worldwide, has recently
been linked to neutrophil activation and release of neutrophil extracellular traps (NETs) via a …
been linked to neutrophil activation and release of neutrophil extracellular traps (NETs) via a …
Specialized regulatory T cells control venous blood clot resolution through SPARC
F Shahneh, A Grill, M Klein… - Blood, The Journal …, 2021 - ashpublications.org
The cells and mechanisms involved in blood clot resorption are only partially known. We
show that regulatory T cells (Tregs) accumulate in venous blood clots and regulate …
show that regulatory T cells (Tregs) accumulate in venous blood clots and regulate …
Endothelial cells: source, barrier, and target of defensive mediators
LT Roumenina, J Rayes, M Frimat… - Immunological …, 2016 - Wiley Online Library
Endothelium is strategically located at the interface between blood and interstitial tissues,
placing thus endothelial cell as a key player in vascular homeostasis. Endothelial cells are …
placing thus endothelial cell as a key player in vascular homeostasis. Endothelial cells are …
Novel biomarkers associated with deep venous thrombosis: a comprehensive review
DM Barnes, TW Wakefield… - Biomarker …, 2008 - journals.sagepub.com
Primary and recurrent venous thromboembolic disease (VTE, deep venous thrombosis and
pulmonary embolism) remain a significant source of morbidity and mortality in the …
pulmonary embolism) remain a significant source of morbidity and mortality in the …
By word of mouse: using animal models in venous thrombosis research
Deep vein thrombosis (DVT) is a disease with high prevalence and morbidity. It can lead to
pulmonary embolism with severe respiratory insufficiency and risk of death. Mechanisms …
pulmonary embolism with severe respiratory insufficiency and risk of death. Mechanisms …
Venous thromboembolism: thrombosis, inflammation, and immunothrombosis for clinicians
E Vazquez-Garza, C Jerjes-Sanchez… - Journal of thrombosis …, 2017 - Springer
Venous thromboembolism (VTE) is a worldwide disease related with mortality,
cardiovascular disability, impaired quality of life and, cause major long-term complications …
cardiovascular disability, impaired quality of life and, cause major long-term complications …
Targeted deletion of CCR2 impairs deep vein thombosis resolution in a mouse model
PK Henke, CG Pearce, DM Moaveni… - The Journal of …, 2006 - journals.aai.org
CCR2 is required for monocyte recruitment in many inflammatory processes, as well as
conferring Th1 lymphokine responses. Deep vein thrombosis (DVT) resolution represents a …
conferring Th1 lymphokine responses. Deep vein thrombosis (DVT) resolution represents a …
Thromboinflammation: from atherosclerosis to COVID-19
DD Wagner, LA Heger - Arteriosclerosis, thrombosis, and vascular …, 2022 - Am Heart Assoc
The activating interplay of thrombosis and inflammation (thromboinflammation) has been
established as a major underlying pathway, driving not only cardiovascular disease but also …
established as a major underlying pathway, driving not only cardiovascular disease but also …
New insights into the mechanisms of venous thrombosis
N Mackman - The Journal of clinical investigation, 2012 - Am Soc Clin Investig
Venous thrombosis is a leading cause of morbidity and mortality in industrialized countries,
especially in the elderly. Many risk factors have been identified for venous thrombosis that …
especially in the elderly. Many risk factors have been identified for venous thrombosis that …