A prospective phase II/III multicenter study of PSMA-targeted 18F-DCFPyL PET/CT imaging in patients with prostate cancer (OSPREY): A sub-analysis of regional and …

F Pouliot, P Carroll, S Probst, KJ Pienta, SP Rowe… - 2020 - ascopubs.org
9 Background: Current imaging modalities are suboptimal for the initial staging of men at risk
of harboring occult metastatic prostate cancer (PCa). PSMA-based imaging is considered …

A prospective phase II/III study of PSMA-targeted 18F-DCFPyL-PET/CT in patients (pts) with prostate cancer (PCa)(OSPREY): A subanalysis of disease staging …

JC Durack, AS Alva, MA Preston, F Pouliot… - 2021 - ascopubs.org
32 Background: Conventional imaging and bone scintigraphy are suboptimal modalities for
identifying PCa. PSMA-based imaging is highly promising for PCa detection. 18F-DCFPyL is …

18F-DCFPyL PET/CT for primary staging in 160 high-risk prostate cancer patients; metastasis detection rate, influence on clinical management and preliminary …

M Wondergem, FM Van Der Zant, WAM Broos… - European Journal of …, 2021 - Springer
Purpose Prostate-specific membrane antigen (PSMA) PET/CT shows better diagnostic
performance for detection of lymph node and bone metastases as compared to conventional …

Results from the OSPREY trial: A prOspective phase 2/3 multi-center study of 18F-DCFPyL PET/CT imaging in patients with pRostate cancer-examination of diagnostic …

S Rowe, M Gorin, K Pienta, B Siegel, P Carroll… - 2019 - Soc Nuclear Med
586 Objectives: Prostate-specific membrane antigen (PSMA) is a transmembrane protein
that is overexpressed by prostate cancer (PCa) cells. PSMA-based imaging is considered …

PSMA-Based [18F]DCFPyL PET/CT Is Superior to Conventional Imaging for Lesion Detection in Patients with Metastatic Prostate Cancer

SP Rowe, KJ Macura, E Mena, AL Blackford… - Molecular imaging and …, 2016 - Springer
Purpose Current standard of care conventional imaging modalities (CIM) such as X-ray
computed tomography (CT) and bone scan can be limited for detection of metastatic prostate …

Role of FDG PET/CT in management of patients with prostate cancer

DEK Sutherland, AA Azad, DG Murphy… - Seminars in nuclear …, 2024 - Elsevier
Prostate cancer is the second most common cancer in men worldwide.[18 F] FDG PET/CT
imaging, a well-known and effective technique for detecting malignancies, has not been …

18F-DCFBC PET/CT for PSMA-based detection and characterization of primary prostate cancer

SP Rowe, KL Gage, SF Faraj, KJ Macura… - Journal of Nuclear …, 2015 - Soc Nuclear Med
We previously demonstrated the ability to detect metastatic prostate cancer using N-[N-[(S)-
1, 3-dicarboxypropyl] carbamoyl]-4-18F-fluorobenzyl-l-cysteine (18F-DCFBC), a low …

Prospective Evaluation of 18F-DCFPyL PET/CT in Detection of High-Risk Localized Prostate Cancer: Comparison With mpMRI

S Gaur, E Mena, SA Harmon… - American Journal of …, 2020 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this study was to assess the utility of PET with (2 S)-2-[[(1 S)-1-
carboxy-5-[(6-(18F) fluoranylpyridine-3-carbonyl) amino] pentyl] carbamoylamino] …

A prospective phase 2/3 multicenter study of 18F-DCFPyL PET/CT imaging in patients with prostate cancer: Examination of diagnostic accuracy (OSPREY).

MJ Morris, P Carroll, S Probst, F Pouliot, L Saperstein… - 2018 - ascopubs.org
TPS5092 Background: Accurate localization of sites of disease is essential for delivering
optimal care to patients with prostate cancer. This is especially true for patients who may …

A prospective comparison of 18F-sodium fluoride PET/CT and PSMA-targeted 18F-DCFBC PET/CT in metastatic prostate cancer

SA Harmon, E Bergvall, E Mena, JH Shih… - Journal of Nuclear …, 2018 - Soc Nuclear Med
The purpose of this study was to compare the diagnostic performance of 18F-DCFBC
PET/CT, a first-generation 18F-labeled prostate-specific membrane antigen (PSMA) …