In this comprehensive review, we will dissect the impact of research on proteoglycans
focusing on recent developments involved in their synthesis, degradation, and interactions …

Proteoglycans have emerged as biomacromolecules with important roles in matrix
remodeling, homeostasis, and signaling in the past two decades. Due to their negatively …

Glycosaminoglycans (GAGs) compose one of four classes of mammalian biopolymers, and
are arguably the most complex. The research areas of glycobiology, glycopolymers, and the …

Proteoglycans (PGs), a family of complex post-translationally sculptured macromolecules,
are fundamental regulators of most normal and aberrant cellular functions. The unparalleled …

The extracellular matrix (ECM) constitutes a highly dynamic three-dimensional structural
network comprised of macromolecules, such as proteoglycans/glycosaminoglycans …

Proteoglycans control numerous normal and pathological processes, among which are
morphogenesis, tissue repair, inflammation, vascularization and cancer metastasis. During …

Immune regulation is a complex biological signaling pathway in which several classes of
biomolecules and small molecules play a complacent role to mediate this process …

Extracellular matrix is a highly dynamic macromolecular network. Proteoglycans are major
components of extracellular matrix playing key roles in its structural organization and cell …

This comprehensive review delves into the intricate landscape of glycans and
glycoconjugates, unraveling their multifaceted roles across diverse biological dimensions …

Circulating tumor cells (CTCs) are accessible by liquid biopsies via an easy blood draw.
They represent not only the primary tumor site, but also potential metastatic lesions, and …