The initial steps in the pathogenesis of atherosclerosis involve changes to the vascular
endothelium, which produces numerous substances involved in the regulation and …

The adhesion molecule P-selectin (CD62P) is of interest because of its role in modulating
interactions between blood cells and the endothelium, and also because of the possible use …

Objective: E-selectin is an endothelial cell-specific membrane glycoprotein that participates
in leukocyte adhesion and has also been suggested to function in angiogenesis. To gain …

The cellular adhesion molecule E-selectin is expressed on activated endothelial cells, and is
involved in the process of adherence of blood cells to vessel endothelium in inflammatory …

Background E-selectin, also known as endothelial cell leukocyte adhesion molecule-1, is a
member of the selectin family of adhesion molecules and is expressed on vascular …

Background: Increased expression of the endothelial leukocyte adhesion molecule E-
selectin is implicated in vascular disease and may accompany the development of …

P-selectin is a 140 kD protein found in the α-granules of platelets and the Weibel-Palade
bodies of endothelial cells. On cell activation it is expressed on the cell surface and also …

Background—Hypercholesterolemia is considered a major risk factor for the development of
atherosclerosis. Enhanced lipid peroxidation and persistent platelet activation can be …

Adhesion molecules like the members of the selectin family participate In the interaction
between leukocytes and the endothellum. They are also involved in the pathogenesis of …

P-selectin is an inflammatory adhesion molecule expressed on activated platelets and
endothelial cells. The role of inflammatory cells and adhesion molecules in the development …