Peripheral immunophenotypes in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection

MJ Carter, M Fish, A Jennings, KJ Doores, P Wellman… - Nature medicine, 2020 - nature.com
Recent reports highlight a new clinical syndrome in children related to severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2)—multisystem inflammatory syndrome in …

Humoral signatures of protective and pathological SARS-CoV-2 infection in children

YC Bartsch, C Wang, T Zohar, S Fischinger, C Atyeo… - Nature medicine, 2021 - nature.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic continues to
spread relentlessly, associated with a high frequency of respiratory failure and mortality …

Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19

K Sacco, R Castagnoli, S Vakkilainen, C Liu… - Nature medicine, 2022 - nature.com
Abstract Pediatric Coronavirus Disease 2019 (pCOVID-19) is rarely severe; however, a
minority of children infected with severe acute respiratory syndrome coronavirus 2 (SARS …

Mapping systemic inflammation and antibody responses in multisystem inflammatory syndrome in children (MIS-C)

CN Gruber, RS Patel, R Trachtman, L Lepow, F Amanat… - Cell, 2020 - cell.com
Initially, children were thought to be spared from disease caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). However, a month into the epidemic, a novel …

Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children

ND Beckmann, PH Comella, E Cheng, L Lepow… - Nature …, 2021 - nature.com
Multisystem inflammatory syndrome in children (MIS-C) presents with fever, inflammation
and pathology of multiple organs in individuals under 21 years of age in the weeks following …

The immunology of multisystem inflammatory syndrome in children with COVID-19

CR Consiglio, N Cotugno, F Sardh, C Pou, D Amodio… - Cell, 2020 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is typically very
mild and often asymptomatic in children. A complication is the rare multisystem inflammatory …

[HTML][HTML] Multisystem inflammatory syndrome in children occurred in one of four thousand children with severe acute respiratory syndrome coronavirus 2

M Holm, UB Hartling, LS Schmidt… - … (Oslo, Norway: 1992), 2021 - ncbi.nlm.nih.gov
Multisystem inflammatory syndrome in children (MIS-C) is a novel disease that is associated
with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). 1 Until now, only …

Polyclonal expansion of TCR Vβ 21.3+ CD4+ and CD8+ T cells is a hallmark of multisystem inflammatory syndrome in children

M Moreews, K Le Gouge, S Khaldi-Plassart… - Science …, 2021 - science.org
Multisystem inflammatory syndrome in children (MIS-C) is a delayed and severe
complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

The immune landscape of SARS-CoV-2-associated Multisystem Inflammatory Syndrome in Children (MIS-C) from acute disease to recovery

E Syrimi, E Fennell, A Richter, P Vrljicak, R Stark, S Ott… - Iscience, 2021 - cell.com
Multisystem inflammatory syndrome in children (MIS-C) is a life-threatening disease
occurring several weeks after severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

[HTML][HTML] Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children

A Ramaswamy, NN Brodsky, TS Sumida, M Comi… - Immunity, 2021 - cell.com
Multisystem inflammatory syndrome in children (MIS-C) is a life-threatening post-infectious
complication occurring unpredictably weeks after mild or asymptomatic SARS-CoV-2 …