It was previously demonstrated that the central nicotinic acetylcholine receptor antagonist
mecamylamine perfused in the ventral tegmental area (VTA) counteracts the elevation of …

Ethanol-induced elevations of accumbal dopamine levels have been linked to the
reinforcing properties of the drug. However, it has not yet been demonstrated where the …

Ethanol-induced accumbal dopamine elevations have been linked to ethanol consumption.
It is unclear, however, where along the mesolimbic dopamine system this effect is initiated …

It has been suggested that ethanol exerts its mesolimbic dopamine activating effects and its
reinforcing effects via interaction with central nicotinic acetylcholine receptors, thus providing …

The mesocorticolimbic dopamine system is believed to be involved in mediating the positive
reinforcing effects of drugs of abuse, including ethanol. The nicotinic acetylcholine receptor …

Aims: Concurrent use of ethanol and nicotine (tobacco) is often seen in human beings. In
previous animal experiments, we have demonstrated that nicotinic acetylcholine receptors …

It has been suggested that ethanol may interact with the central nicotinic acetylcholine
receptor, thus providing a basis for the often observed high consumption of both ethanol and …

Background: Alcoholism is associated with a higher incidence of smoking. The mesolimbic
dopaminergic pathway is believed to play an important role in the reinforcing effects of both …

Aims: Ethanol (EtOH) activates the mesolimbic dopamine system and increases dopamine
levels in the nucleus accumbens (nAc), which is believed to underlie the rewarding effects of …

The actions of ethanol on extracellular dopamine levels in the n. accumbens were examined
in both anesthetized and unanesthetized rats using either in vivo voltammetry or …