Evaluation of assays to measure aminoglycosides in serum: comparison of accuracy and precision based on external quality assessment

M Li, L Ma, C Chen, L Lei, X Zhai, D Luo… - Therapeutic Drug …, 2020 - journals.lww.com
Background: Aminoglycosides require highly accurate therapeutic drug monitoring owing to
their narrow therapeutic windows and toxic side effects. Therapeutic drug monitoring varies …

Therapeutic drug monitoring for aminoglycosides: not yet readily available in Japanese university hospitals

H Hagiya, F Otsuka - JMA journal, 2021 - jstage.jst.go.jp
As leading hospitals, national and public university hospitals have a mission to treat a large
number of patients with intractable and/or critical diseases. Aminoglycosides broadly cover …

Aminoglycoside usage and monitoring in a Saudi Arabian teaching hospital: a ten‐year laboratory audit

Bahar, MEBK Ahmed - Journal of clinical pharmacy and …, 2000 - Wiley Online Library
Background and objective: In 1989, a therapeutic drug monitoring service was established
in Assir Central Hospital, Abha, Saudi Arabia, by the Department of Clinical Pharmacology …

The aminoglycoside panel: a new approach to monitoring aminoglycoside therapy

JE Gorsky, JR Latts - Therapeutic Drug Monitoring, 1983 - journals.lww.com
The aminoglycoside antibiotics gentamicin and tobramycin have been monitored
traditionally by measuring peak and trough drug levels in serum. We found interpretation of …

Monitoring aminoglycosides in an intensive care unit

D Commandeur, S Eyrieux, A Le Noël… - Medecine et Maladies …, 2009 - europepmc.org
Objectives This monocentric, observational and retrospective survey was performed to
check the appropriateness between aminoglycoside prescriptions and inhibitor quotient to …

Advances in clinical antibiotic testing

KM Rentsch - Advances in Clinical Chemistry, 2022 - Elsevier
Although the measurement of aminoglycosides and glycopeptides in blood has been well
established, it has become evident that therapeutic drug monitoring (TDM) should be …

Evaluation of commercial assays for vancomycin and aminoglycosides in serum: a comparison of accuracy and precision based on external quality assessment

JF Wilson, AC Davis, CM Tobin - Journal of Antimicrobial …, 2003 - academic.oup.com
Objective: To compare the accuracy and precision of commercial assay techniques in the
measurement of gentamicin, tobramycin, amikacin, netilmicin and vancomycin in serum …

Automated homogeneous immunoassay for gentamicin on the dimension clinical chemistry system

TQ Wei, VP Chu, AR Craig, JE Duffy… - Clinical …, 1999 - academic.oup.com
Background: Monitoring of the concentration of gentamicin in serum and plasma during
therapy is widely recommended and practiced in hospitals. Our aim was to develop a …

Monitoring aminoglycoside therapy

RE Mullins, V Lampasona, RB Conn - Clinics in Laboratory Medicine, 1987 - Elsevier
The aminoglycoside antibiotics are indispensible therapeutic agents; however, a high
incidence of toxic effects mandates that they be used with caution. Monitoring of serum …

Assays for therapeutic monitoring and pharmacokinetic investigations of aminoglycosides: quality aspects

LO White - Therapeutic drug monitoring, 1998 - journals.lww.com
Clinical laboratory investigations used to aid antimicrobial chemotherapy of serious infection
include routine sensitivity testing and, in the case of those drugs with a narrow therapeutic …