Somatotropic‐Testicular Axis: A crosstalk between GH/IGF‐I and gonadal hormones during development, transition, and adult age
M Tenuta, F Carlomagno, B Cangiano, G Kanakis… - …, 2021 - Wiley Online Library
Background The hypothalamic‐pituitary‐gonadal (HPG) and hypothalamic‐pituitary‐
somatotropic (HPS) axes are strongly interconnected. Interactions between these axes are …
somatotropic (HPS) axes are strongly interconnected. Interactions between these axes are …
Testicular growth and pubertal onset in GH-deficient children treated with growth hormone: a retrospective study
R Cannarella, M Caruso, A Crafa… - Frontiers in …, 2021 - frontiersin.org
The prevalence of idiopathic oligozoospermia has been esteemed as high as 75%. An
Italian survey has reported bilateral testicular hypotrophy in 14% of final-year high school …
Italian survey has reported bilateral testicular hypotrophy in 14% of final-year high school …
Why do normal children have acromegalic levels of IGF-I during puberty?
A Juul, NE Skakkebæk - The Journal of Clinical Endocrinology & …, 2019 - academic.oup.com
Context The rapid pubertal height growth is unique to humans, but why do we have it?
Although the spurt contributes 13% to 15% to the final adult height, we hypothesized that the …
Although the spurt contributes 13% to 15% to the final adult height, we hypothesized that the …
Common features and differences of the hypothalamic–pituitary–gonadal axis in male and female
Male and female reproductive axis, comprised of hypothalamus, pituitary and gonads,
present common features and differences, discussed in this review. These include the way …
present common features and differences, discussed in this review. These include the way …
Puberty is delayed in male growth hormone receptor gene—disrupted mice
DE Keene, MO Suescun, MG Bostwick… - Journal of …, 2002 - Wiley Online Library
The role of insulin‐like growth factor‐I (IGF‐I) in the initiation of puberty and testicular
function is poorly understood. Growth hormone (GH) receptor (R) gene‐disrupted mice or …
function is poorly understood. Growth hormone (GH) receptor (R) gene‐disrupted mice or …
Effects of growth hormone replacement therapy on IGF-related parameters and on the pituitary-gonadal axis in GH-deficient males: a double-blind, placebo-controlled …
A Juul, AM Andersson, SA Pedersen… - Hormone Research in …, 1998 - karger.com
It has been suggested that growth hormone (GH) may play a regulatory role in male
reproductive function. To express full anabolic effect in immature boys testosterone …
reproductive function. To express full anabolic effect in immature boys testosterone …
Molecular regulation of hypothalamus–pituitary–gonads axis in males
JM Jin, WX Yang - Gene, 2014 - Elsevier
The hypothalamic–pituitary–gonadal axis (HPG) plays vital roles in reproduction and steroid
hormone production in both sexes. The focus of this review is upon gene structures, receptor …
hormone production in both sexes. The focus of this review is upon gene structures, receptor …
[PDF][PDF] Hypothalamus-PituitaryGonadal axis: It is time for revision
B Asimakopoulos - Hum Genet Embryol, 2012 - academia.edu
The structure and the function of the Hypothalamus-Pituitary-Gonadal (HPG) axis is an
integral part of the knowledge on the physiology of the human body that every bioscientist …
integral part of the knowledge on the physiology of the human body that every bioscientist …
Postnatal changes in testicular position are associated with IGF-I and function of Sertoli and Leydig cells
JJ Koskenniemi, HE Virtanen… - The Journal of …, 2018 - academic.oup.com
Context Despite clinical guidelines calling for repetitive examination of testicular position
during childhood, little is known of normal changes in testicular position during childhood, let …
during childhood, little is known of normal changes in testicular position during childhood, let …
Regulation of testicular insulin-like growth factor-I in pubertal growth hormone-deficient male rats
J Spiteri-Grech, JMS Bartlett… - Journal of …, 1991 - joe.bioscientifica.com
ABSTRACT GH plays a major role in pubertal growth, effects mainly mediated by stimulation
of insulin-like growth factor-I (IGF-I) production by the liver. However, the role of GH in the …
of insulin-like growth factor-I (IGF-I) production by the liver. However, the role of GH in the …