Proteins and RNA are used as enzymes in nature, while DNA is used for the storage and
transfer of genetic information. Proteins and RNA are biopolymers that can fold into complex …

Proteins and RNA are known to be enzymes in nature. These biopolymers have complex
secondary and tertiary structures that can enable substrate binding and catalysis. DNA is …

We report DNA catalysts (deoxyribozymes) that join tyrosine‐containing peptides to RNA
and DNA in one step and without requiring protecting groups on either the peptide or the …

Gene therapy, siRNA, and therapeutic aptamers attract great interest owing to their versatility
to treat a wide range of diseases and their potential high selectivity. Unfortunately …

This study focuses on the development of DNA catalysts (deoxyribozymes) that modify side
chains of peptide substrates, with the long-term goal of achieving DNA-catalyzed covalent …

We show that DNA enzymes (deoxyribozymes) can introduce azide functional groups at
tyrosine residues in peptide substrates. Using in vitro selection, we identified …

Deoxyribozymes (DNA enzymes) have been developed for a growing variety of chemical
reactions, including with peptide substrates. We recently described the first tyrosine kinase …

Deoxyribozymes are particular DNA sequences that have catalytic ability, analogous to
protein enzymes as functional amino acid sequences.[1, 2] The discovery of natural RNA …

Nature has developed the use of proteins and RNA as enzymes, while DNA is used for the
storage and transfer of genetic information. Proteins and RNA are biopolymers that can fold …

Conspectus Catalysis is a fundamental chemical concept, and many kinds of catalysts have
considerable practical value. Developing entirely new catalysts is an exciting challenge …