Objective The present study aims to evaluate the impact of Astilbin (AST) on cortical neuron
survival in vitro under conditions of oxygen-glucose deprivation and reoxygenation (OGD/R) …

Sulforaphane, a naturally occurring compound found in cruciferous vegetables, has been
shown to be neuroprotective in several neurological disorders. In this study, we sought to …

Cerebral ischemia/reperfusion (I/R) injury is a brain injury following ischaemic stroke that is
associated with oxidative stress. Taraxasterol, a natural product, has been shown to have …

Traumatic brain injury (TBI) is a serious public health and medical problem worldwide.
Oxidative stress plays a vital role in the pathogenesis of TBI. Nuclear factor erythroid 2 …

Objectives Our study verified the neuroprotective properties of emodin against oxygen-
glucose deprivation/reoxygenation (OGD/R) and demonstrated its mechanism. Methods …

Mitoquinone (MitoQ) is a powerful mitochondrial-targeted antioxidant whose neuroprotective
effects have been shown in a variety of animal models of neurological diseases. However …

Aim: To determine whether Nrf2 signaling pathway activation could attenuate oxidative
stress and neuronal damage following traumatic brain injury (TBI). Methods: Controlled …

Background Mounting evidence shows that urate may become a biomarker of Parkinson's
disease (PD) diagnosis and prognosis and a neuroprotectant candidate for PD therapy …

Nuclear factor E2-related factor 2 (Nrf2)/antioxidant response element (ARE) pathway is an
important cellular stress response pathway involved in neuroprotection. We previously …

Cryptotanshinone (CPT), a terpenoid isolated from the roots of Salvia miltiorrhiza Bunge,
was reported to have neuroprotective effects against cerebral ischemic stroke. However, the …