Rationale Diffusion tensor imaging has been used before in testing associations between
cigarette smoking and white matter integrity, with inconsistent results. Published reports …

Results from recent studies suggest that chronic cigarette smoking is associated with
increased white matter volume in the brain as determined by in vivo neuroimaging. We used …

Previous diffusion tensor imaging (DTI) studies revealed contradictory effects of smoking on
fractional anisotropy (FA). Multiple DTI‐derived indices may help to deduce the …

BACKGROUND: Abnormal macrostructural brain abnormalities in both gray matter and
white matter have been reported in cigarette smokers. However, less is known about white …

Background Tobacco use remains the most preventable cause of death; however, its effects
on the brain, and particularly white matter, remain elusive. Previous diffusion tensor imaging …

Cigarette smoking doubles the risk of dementia and Alzheimer's disease. Various
pathophysiological pathways have been proposed to cause such a cognitive decline, but the …

Background We previously reported widespread microstructural deficits of brain white matter
in alcohol-dependent individuals (ALC) compared to light drinkers in a small 1.5 T diffusion …

In the present study, we aimed to investigate the difference in white matter between smokers
and nonsmokers. In addition, we examined relationships between white matter integrity and …

Individuals who abuse substances often differ from nonusers in their brain structure.
Substance abuse and addiction is often associated with atrophy and pathology of grey …

Background Adolescence and young adulthood are critical vulnerability periods for initiation
of tobacco smoking. White matter development is ongoing during this time and may be …