Cu, Zn, I-Doped Carbon Dots with Boosted Triple Antioxidant Nanozyme Activity for Treatment of DSS-Induced Colitis

Y Cui, D Yang, Q Li, Z Peng, Z Zhong… - … Applied Materials & …, 2024 - ACS Publications
Nanozyme-mediated antioxidative therapy is a promising star for treating a myriad of
important diseases through eliminating excessive reactive oxygen species (ROS) such as …

Versatile carbon dots with superoxide dismutase-like nanozyme activity and red fluorescence for inflammatory bowel disease therapeutics

Y Ma, J Zhao, L Cheng, C Li, X Yan, Z Deng, Y Zhang… - Carbon, 2023 - Elsevier
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease
(CD), is a chronic and recurrent disease that seriously affects the life quality of patients …

Oral carbon dot nanozymes with red fluorescence and superoxide dismutase-like activity for colitis bioimaging and inflammation management

M Zhang, Y Liang, Y Zhang, L Zhang, N Wang… - Chemical Engineering …, 2024 - Elsevier
Disturbed intestinal microbiota and abnormally high levels of reactive oxygen species (ROS)
in the colon are important factors in the pathogenesis of ulcerative colitis (UC). Therefore …

Biomimetic MOF nanoparticles delivery of C-dot nanozyme and CRISPR/Cas9 system for site-specific treatment of ulcerative colitis

Y Ma, W Gao, Y Zhang, M Yang, X Yan… - … Applied Materials & …, 2022 - ACS Publications
Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) of unknown etiology
affecting the colon and rectum. Previous studies have found that reactive oxygen species …

Natural medicines-derived carbon dots as novel oral antioxidant administration strategy for ulcerative colitis therapy

T Wu, X Bai, Y Zhang, E Dai, J Ma, C Yu, C He… - Journal of …, 2024 - Springer
Background Ulcerative colitis (UC) is a chronic intestinal inflammation, resulting in a global
healthcare challenge with no real specific medicine. Natural medicines are recognized as a …

Protective effect of carbon dots as antioxidants on intestinal inflammation by regulating oxidative stress and gut microbiota in nematodes and mouse models

N Peng, J Wang, H Zhu, Z Liu, J Ren, W Li… - International …, 2024 - Elsevier
Inflammatory bowel disease (IBD) is a recurrent chronic colitis disease with increasing
incidence and prevalence year by year. The single efficacy and significant side effects of …

Self-assembled copper herbal carbon dots nanosheets with powerful antibacterial properties: A robust cascade antioxidant nanozyme for scavenging reactive oxygen …

J Deng, B Zhang, Y Zhong, D Fu, A Zhu, X Liu - Chemical Engineering …, 2024 - Elsevier
Oxidative stress is a growing concern, necessitating more effective antioxidants for complex
environments. Herein, we developed a composite nanozyme, DVI-CDs-Cu, with exceptional …

Carbon dots nanozyme for anti-inflammatory therapy via scavenging intracellular reactive oxygen species

C Dong, X Ma, Y Huang, Y Zhang… - Frontiers in Bioengineering …, 2022 - frontiersin.org
Developing an efficient antioxidant for anti-inflammatory therapy via scavenging reactive
oxygen species (ROS) remains a great challenge owing to the insufficient activity and …

Ultrasmall copper-based nanoparticles for reactive oxygen species scavenging and alleviation of inflammation related diseases

T Liu, B Xiao, F Xiang, J Tan, Z Chen, X Zhang… - Nature …, 2020 - nature.com
Oxidative stress is associated with many acute and chronic inflammatory diseases, yet
limited treatment is currently available clinically. The development of enzyme-mimicking …

Orally biomimetic metal-phenolic nanozyme with quadruple safeguards for intestinal homeostasis to ameliorate ulcerative colitis

Y Zhu, X Huang, Z Deng, T Bai, B Gao, C Xu… - Journal of …, 2024 - Springer
Background Ulcerative colitis (UC) is defined by persistent inflammatory processes within
the gastrointestinal tract of uncertain etiology. Current therapeutic approaches are limited in …