Facial and ocular deposition of nebulized budesonide: effects of face mask design

KW Harris, GC Smaldone - Chest, 2008 - Elsevier
Background In vivo case reports and in vitro studies have indicated that aerosol therapy
using face masks can result in drug deposition on the face and in the eyes, and that face …

Facemask design, facial deposition, and delivered dose of nebulized aerosols

GC Smaldone, S Sangwan, A Shah - Journal of aerosol medicine, 2007 - liebertpub.com
Nebulizers are often interfaced to patients using facemasks, especially when the patient is
sick and uncooperative. Tight-fitting masks are thought to improve drug delivery, but recent …

Facemasks and facial deposition of aerosols

S Sangwan, BK Gurses, GC Smaldone - Pediatric pulmonology, 2004 - Wiley Online Library
Passage of aerosol around or through a facemask can result in deposition on the face and in
the eyes. The present study quantified facial and eye deposition in a model simulating drug …

Breath-synchronized nebulization diminishes the impact of patient-device interfaces (face mask or mouthpiece) on the inhaled mass of nebulized budesonide

K Nikander, L Agertoft, S Pedersen - Journal of Asthma, 2000 - Taylor & Francis
The choice of patient-device interface (face mask or mouthpiece) influences the inhaled
mass and the lung deposition of nebulized drugs. The use of a mouthpiece has been shown …

[HTML][HTML] Aerosol delivery of nebulised budesonide in young children with asthma

KG Schueepp, SG Devadason, C Roller… - Respiratory …, 2009 - Elsevier
BACKGROUND: Lung deposition of inhaled steroids, likely to be of benefit in the anti-
inflammatory treatment of asthma in young children, is low. This is explained by age specific …

Variation in pediatric aerosol delivery: importance of facemask

GC Smaldone, E Berg, K Nikander - Journal of aerosol medicine, 2005 - liebertpub.com
We have quantified in vitro the influence of the facemask on the amount of drug delivered
(eg, inhaled mass) by jet nebulizer and pressurized metered dose inhaler (pMDI) valved …

Redesigned face mask improves “real life” aerosol delivery for Nebuchamber

I Amirav, Y Mansour, A Mandelberg… - Pediatric …, 2004 - Wiley Online Library
The currently available facemask interface for the Nebuchamber (N) valved‐holding
chamber (VHC) provides a very poor seal to the face, which, on average, decreases the …

In vitro delivery of budesonide from 30 jet nebulizer/compressor combinations using infant and child breathing patterns

EB Berg, RJ Picard - Respiratory care, 2009 - rc.rcjournal.com
BACKGROUND: An aerosol of budesonide inhalation suspension is delivered when used
with various jet-nebulizer/compressor combinations. The constant introduction of new …

Metered dose inhaler add-on devices: is the inhaled mass of drug dependent on the size of the infant?

M Turpeinen, K Nikander, LP Malmberg… - Journal of aerosol …, 1999 - liebertpub.com
Limited cooperation and low tidal volumes in infants make aerosol therapy difficult. We
measured the amount of drug delivered from two baby spacer devices especially developed …

An in vitro analysis of the output of budesonide from different nebulizers

PW Barry, C O'Callaghan - Journal of allergy and clinical immunology, 1999 - Elsevier
Background: Inhaled corticosteroids are increasingly used in the treatment of asthma, and
many different nebulizers are available to aerosolize steroid medications. There are few …