VA Cooperative Study# 75 was established to test in a controlled, randomized trial the
hypothesis that warfarin anticoagulation would favorably affect the course of certain types of …

Anticoagulants have been demonstrated to reduce tumor growth in certain experimental
animal systems. Inhibition of clot formation interferes with tumor growth and spread while …

Background The length of time after an episode of venous thromboembolism during which
the risk of newly diagnosed cancer is increased is not known, and whether vitamin K …

A study was made on the effect of warfarin-induced anticoagulation on the ability of KHT
sarcoma cells to metastasize in syngeneic C3H mice. This anticoagulant effectively reduced …

Parenteral anticoagulation for prolonging survival in patients with cancer who have no other
indication for anticoagulation Page 1 Parenteral anticoagulation for prolonging survival in patients …

Malignancy is a risk factor for thromboembolism and anti-cancer chemotherapy can increase
this risk. Prophylaxis of thrombosis with very-low-dose warfarin given concurrently with …

Routine blood coagulation tests were performed on 431 consecutive patients enrolled in a
study of the role of anticoagulation in cancer treatment (VA Cooperative Study# 75). Two …

Background The use of warfarin sodium for treating venous thromboembolism in patients
with cancer is associated with a significant risk of recurrence and bleeding. The use of low …

Metastasis involves several distinct steps, including one in which the tumor cell, after entry
into the bloodstream, comes to rest in a capillary located at the distant site where a …

Abstract Learning Objectives After completing this course, the reader will be able to: Define
characteristics of the interface between deep vein thrombosis and malignancy. Evaluate …