[HTML][HTML] Episodic withdrawal promotes psychomotor sensitization to morphine

PE Rothwell, JC Gewirtz, MJ Thomas - Neuropsychopharmacology, 2010 - nature.com
The relative intermittency or continuity of drug delivery is a major determinant of addictive
liability, and also influences the impact of drug exposure on brain function and behavior …

Trait impulsivity predicts escalation of sucrose seeking and hypersensitivity to sucrose-associated stimuli.

L Diergaarde, T Pattij, L Nawijn… - Behavioral …, 2009 - psycnet.apa.org
Poor impulse control has been associated with compulsive drug seeking and an enhanced
risk of relapse, suggesting that impulsivity is causally related to addiction proneness and …

[HTML][HTML] Impulsivity and response inhibition in alcohol dependence and problem gambling

AJ Lawrence, J Luty, NA Bogdan, BJ Sahakian… - …, 2009 - Springer
Introduction Impulsivity is a central feature of drug addiction and may arise as a result of
impaired inhibitory control. The extent to which inhibitory deficits arise as a consequence of …

Selective norepinephrine reuptake inhibition by atomoxetine prevents cue-induced heroin and cocaine seeking

D Economidou, JW Dalley, BJ Everitt - Biological psychiatry, 2011 - Elsevier
BACKGROUND:: Preventing relapse to drug use is a major challenge for drug addiction
treatment. We have recently shown that impulsivity predating drug-taking increases the …

Highly impulsive rats: modelling an endophenotype to determine the neurobiological, genetic and environmental mechanisms of addiction

B Jupp, D Caprioli, JW Dalley - Disease models & …, 2013 - journals.biologists.com
Impulsivity describes the tendency of an individual to act prematurely without foresight and is
associated with a number of neuropsychiatric co-morbidities, including drug addiction. As …

Which came first: Cannabis use or deficits in impulse control?

L Rinehart, S Spencer - Progress in Neuro-Psychopharmacology and …, 2021 - Elsevier
Impulse control deficits are often found to co-occur with substance use disorders (SUDs). On
the one hand, it is well known that chronic intake of drugs of abuse remodels the brain with …

Neurobiology of craving, conditioned reward and relapse

F Weiss - Current opinion in pharmacology, 2005 - Elsevier
Chronic vulnerability to relapse is a formidable challenge for the treatment of drug addiction.
The neurobiological basis of relapse and its prevention has, therefore, attracted major …

Impulsivity predicts individual susceptibility to high levels of alcohol self-administration

CX Poulos, AD Le, JL Parker - Behavioural pharmacology, 1995 - journals.lww.com
Clinical studies indicate large individual differences in susceptibility to alcohol abuse. Poor
behavioral self regulation has been proposed to reflect a predisposing factor. Like humans …

Impulsivity as a vulnerability factor for poor addiction treatment outcomes: a review of neurocognitive findings among individuals with substance use disorders

L Stevens, A Verdejo-García, AE Goudriaan… - Journal of substance …, 2014 - Elsevier
With the current review, we explore the hypothesis that individual differences in
neurocognitive aspects of impulsivity (ie, cognitive and motor disinhibition, delay discounting …

Impulsivity and substance abuse: what is the connection?

FG Moeller, DM Dougherty - Addictive Disorders & Their …, 2002 - journals.lww.com
The role of impulsivity in substance abuse has recently received increased attention from
both researchers and clinicians. Although past studies and treatment primarily focused on …