Assessing susceptibility to age-related macular degeneration with genetic markers and environmental factors
Y Chen, J Zeng, C Zhao, K Wang, E Trood… - Archives of …, 2011 - jamanetwork.com
Objectives To evaluate the independent and joint effects of genetic factors and
environmental variables on advanced forms of age-related macular degeneration (AMD) …
environmental variables on advanced forms of age-related macular degeneration (AMD) …
Rare and common genetic variants, smoking, and body mass index: progression and earlier age of developing advanced age-related macular degeneration
JM Seddon, R Widjajahakim… - … Ophthalmology & Visual …, 2020 - iovs.arvojournals.org
Purpose: To determine behavioral and genetic factors associated with incidence and age of
progression to advanced age-related macular degeneration (AMD), geographic atrophy …
progression to advanced age-related macular degeneration (AMD), geographic atrophy …
[HTML][HTML] Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables
JM Seddon, R Reynolds, J Maller… - … & visual science, 2009 - arvojournals.org
purpose. The joint effects of genetic, ocular, and environmental variables were evaluated
and predictive models for prevalence and incidence of AMD were assessed. methods …
and predictive models for prevalence and incidence of AMD were assessed. methods …
Risk assessment model for development of advanced age-related macular degeneration
ML Klein, PJ Francis, FL Ferris, SC Hamon… - Archives of …, 2011 - jamanetwork.com
Objective To design a risk assessment model for development of advanced age-related
macular degeneration (AMD) incorporating phenotypic, demographic, environmental, and …
macular degeneration (AMD) incorporating phenotypic, demographic, environmental, and …
[HTML][HTML] Genetic risk factors and age-related macular degeneration (AMD)
M Mousavi, RA Armstrong - Journal of Optometry, 2013 - Elsevier
Age related macular degeneration (AMD) is the leading cause of blindness in individuals
older than 65 years of age. It is a multifactorial disorder and identification of risk factors …
older than 65 years of age. It is a multifactorial disorder and identification of risk factors …
Risk prediction for progression of macular degeneration: 10 common and rare genetic variants, demographic, environmental, and macular covariates
JM Seddon, RE Silver, M Kwong… - … ophthalmology & visual …, 2015 - iovs.arvojournals.org
Purpose.: To determine the association between genetic variants and transition to advanced
age-related macular degeneration (AMD), and to develop a predictive model and online …
age-related macular degeneration (AMD), and to develop a predictive model and online …
A prospective study of 2 major age-related macular degeneration susceptibility alleles and interactions with modifiable risk factors
DA Schaumberg, SE Hankinson, Q Guo… - Archives of …, 2007 - jamanetwork.com
Objectives To delineate the magnitude of susceptibility to age-related macular degeneration
(AMD) due to common variants in the gene for complement factor H (CFH) and the predicted …
(AMD) due to common variants in the gene for complement factor H (CFH) and the predicted …
Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes
PURPOSE: To investigate whether the 2 subtypes of advanced age-related macular
degeneration (AMD), choroidal neovascularization (CNV), and geographic atrophy (GA) …
degeneration (AMD), choroidal neovascularization (CNV), and geographic atrophy (GA) …
The application of genetic risk scores in age-related macular degeneration: a review
Age-related macular degeneration (AMD), a highly prevalent and impactful disease of aging,
is inarguably influenced by complex interactions between genetic and environmental …
is inarguably influenced by complex interactions between genetic and environmental …
Five-year incidence, progression, and risk factors for age-related macular degeneration: the age, gene/environment susceptibility study
F Jonasson, DE Fisher, G Eiriksdottir, S Sigurdsson… - Ophthalmology, 2014 - Elsevier
Objective To investigate the incidence and progression of age-related macular degeneration
(AMD) and associated risk factors. Design Population-based, prospective, cohort study …
(AMD) and associated risk factors. Design Population-based, prospective, cohort study …
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