REM sleep behavior disorder: motor manifestations and pathophysiology

I Arnulf - Movement Disorders, 2012 - Wiley Online Library
Patients with REM sleep behavior disorder (RBD) enact violent dreams during REM sleep in
the absence of normal muscle atonia. This disorder is highly frequent in patients with …

The risk of neurodegeneration in REM sleep behavior disorder: a systematic review and meta-analysis of longitudinal studies

A Galbiati, L Verga, E Giora, M Zucconi… - Sleep medicine …, 2019 - Elsevier
Several studies report an association between REM Sleep Behavior Disorder (RBD) and
neurodegenerative diseases, in particular synucleinopathies. Interestingly, the onset of RBD …

Propagated α-synucleinopathy recapitulates REM sleep behaviour disorder followed by parkinsonian phenotypes in mice

Y Shen, WB Yu, B Shen, H Dong, J Zhao, YL Tang… - Brain, 2020 - academic.oup.com
Idiopathic rapid eye movement sleep behaviour disorder (RBD) is now recognized as an
early manifestation of α-synucleinopathies. Increasing experimental studies demonstrate …

Rapid eye movement sleep behavior disorder: devising controlled active treatment studies for symptomatic and neuroprotective therapy—a consensus statement from …

CH Schenck, JY Montplaisir, B Frauscher, B Hogl… - Sleep medicine, 2013 - Elsevier
Objectives We aimed to provide a consensus statement by the International Rapid Eye
Movement Sleep Behavior Disorder Study Group (IRBD-SG) on devising controlled active …

Rapid eye movement sleep behavior disorder and neurodegenerative disease

MJ Howell, CH Schenck - JAMA neurology, 2015 - jamanetwork.com
Importance The dream enactment of rapid eye movement sleep behavior disorder (RBD) is
often the first indication of an impending α-synuclein disorder, such as Parkinson disease …

The clinical phenotype of idiopathic rapid eye movement sleep behavior disorder at presentation: a study in 203 consecutive patients

A Fernández-Arcos, A Iranzo, M Serradell, C Gaig… - Sleep, 2016 - academic.oup.com
Objective To describe the clinical phenotype of idiopathic rapid eye movement (REM) sleep
behavior disorder (IRBD) at presentation in a sleep center. Methods Clinical history review …

Parkinson risk in idiopathic REM sleep behavior disorder: preparing for neuroprotective trials

RB Postuma, JF Gagnon, JA Bertrand… - Neurology, 2015 - AAN Enterprises
Objective: To precisely delineate clinical risk factors for conversion from idiopathic REM
sleep behavior disorder (RBD) to Parkinson disease, dementia with Lewy bodies, and …

Rapid eye movement sleep parasomnias

CH Schenck, MW Mahowald - Neurologic clinics, 2005 - neurologic.theclinics.com
Classification of the parasomnias includes primary and secondary sleep phenomena that
can emerge throughout the sleep cycle. Rapid eye movement (REM) sleep behavior …

REM sleep behavior disorder in 703 sleep-disorder patients: the importance of eliciting a comprehensive sleep history

B Frauscher, V Gschliesser, E Brandauer, I Marti… - Sleep medicine, 2010 - Elsevier
OBJECTIVES: The aim of our study was to evaluate the frequency of REM sleep behavior
disorder (RBD) in a mixed sleep laboratory population and to assess potential associations …

Characterization of patients with longstanding idiopathic REM sleep behavior disorder

A Iranzo, A Stefani, M Serradell, MJ Martí, F Lomeña… - Neurology, 2017 - AAN Enterprises
Objective: To evaluate the presence of prodromal markers of Parkinson disease (PD) in
patients with longstanding idiopathic REM sleep behavior disorder (IRBD), a small subgroup …