[HTML][HTML] Patients with isolated REM-sleep behavior disorder have elevated levels of alpha-synuclein aggregates in stool

A Schaffrath, S Schleyken, A Seger, H Jergas… - npj Parkinson's …, 2023 - nature.com
Misfolded and aggregated α-synuclein is a neuropathological hallmark of Parkinson's
disease (PD). Thus, α-synuclein aggregates are regarded as a biomarker for the …

Rapid eye movement sleep behavior disorder as a biomarker for neurodegeneration: the past 10 years

RB Postuma, JF Gagnon, J Montplaisir - Sleep medicine, 2013 - Elsevier
Since its original description, idiopathic rapid eye movement sleep behavior disorder (RBD)
has become a well-established risk factor for neurodegenerative disease. Studies from …

Risk factors for possible REM sleep behavior disorder: a CLSA population-based cohort study

C Yao, SM Fereshtehnejad, MR Keezer, C Wolfson… - Neurology, 2019 - AAN Enterprises
Objective To assess sociodemographic, socioeconomic, and clinical correlates of idiopathic
REM sleep behavior disorder (RBD) in a 30,097-person national cohort. Methods …