High-density tissue microarrays (TMA) are useful for profiling protein expression in a large
number of samples but their use for clinical biomarker studies may be limited in …

A rapidly increasing number of genes are being suspected to play a role in cancer biology.
To evaluate the clinical significance of newly detected potential cancer genes, it is usually …

Tissue microarray (TMA) is a recently implemented, high-throughput technology for the
analysis of molecular markers in oncology. This research tool permits the rapid assessment …

Advances in genomics and proteomics are dramatically increasing the need to evaluate
large numbers of molecular targets for their diagnostic, predictive or prognostic value in …

Tissue microarray (TMA) technology is a high-throughput research tool, which has greatly
facilitated and accelerated tissue analyses by in-situ technologies. TMAs are amenable to …

Tissue microarray (TMA) technology allows a massive acceleration of studies correlating
molecular in situ findings with clinico‐pathological information. In this technique, cylindrical …

Background: Molecular signatures in cancer tissue may be useful for diagnosis and are
associated with survival. We used results from high-density tissue microarrays (TMAs) to …

Several investigators have reported the correlation of p53 and bcl-2 immunoreactivity with
post operative prostate specific antigen (PSA) recurrence. Focal and or clustered expression …

The creation of tissue microarrays (TMAs) allows for the rapid immunohistochemical
analysis of thousands of tissue samples, with numerous different antibodies per sample …

Recent research in molecular biology has identified a significant number of novel markers,
which may have diagnostic, prognostic and therapeutic significance. This is particularly …