The action of galanin in the central nervous system is mediated by at least three galanin
receptor subtypes (GalR1, GalR2 and GalR3) which belong to the family of G protein …

There is currently some debate over a possible role of galanin in pain processing. It was
recently reported that the levels of galanin in dorsal root ganglia (DRGs) seem related to …

Publisher Summary This chapter reviews current knowledge of the distribution of GALRs
with a particular focus on the rat CNS. Galanin is a 29 amino acid peptide that is widely …

Single ligature nerve constriction (SLNC) is a newly developed animal model for the study of
neuropathic pain. SLNC of the rat sciatic nerve induces pain-related behaviors, as well as …

Neuropeptide expression in primary sensory neurons is highly plastic in response to
peripheral nerve axotomy. While neuropeptide changes following complete sciatic nerve …

Galanin, acting at the GalR1-3 subtypes of galanin receptors, is involved in the regulation of
cognition, mood, feeding, seizure activity and pain. The understanding of galanin's effects in …

The neuropeptide galanin is expressed developmentally in the dorsal root ganglion (DRG)
and is rapidly up-regulated 120-fold after peripheral nerve section in the adult. Here we …

The neuropeptide galanin may have a role in spinal nociception. In this study, we examined
the excitability of the flexor reflex and its sensitization by repetitive stimulation of nociceptive …

Background: Galanin is expressed in a small percentage of intact small diameter sensory
neurons of the dorsal root ganglia and in the afferent terminals of the superficial lamina of …

This study was conducted to examine the excitability of the nociceptive flexor reflex and its
sensitization by repetitive stimulation of C-fibers in anesthetized mice that lack the galanin …