Evidence suggests that eosinophilic airway inflammation is important in the pathogenesis of
severe chronic obstructive pulmonary disease (COPD) exacerbations. The present authors …

Chronic obstructive pulmonary disease is a common condition and a major cause of
mortality. COPD is characterized by irreversible airflow obstruction. The physiological …

Eosinophilic inflammation is thought to be a characteristic feature of asthma rather than
COPD. However, studies have shown that a subset of COPD patients with eosinophilic …

Background Some patients with chronic obstructive pulmonary disease (COPD) respond to
corticosteroid therapy. Whether these patients have different airway pathology from other …

COPD is a significant cause of morbidity and mortality. In some patients with COPD,
eosinophils contribute to inflammation that promotes airway obstruction; approximately a …

Post hoc and pre-specified analyses of chronic obstructive pulmonary disease (COPD)
randomised controlled trials have shown that higher blood eosinophil counts predict greater …

The heterogeneity of chronic obstructive pulmonary disease (COPD) creates many
diagnostic, prognostic, treatment and management challenges, as the pathogenesis of …

Exacerbations in chronic obstructive pulmonary disease (COPD) are major contributors to
worsening lung function, impaired quality of life, emergency healthcare use and COPD …

Background Eosinophilic airway inflammation characterizes a chronic obstructive pulmonary
disease (COPD) phenotype that requires more study. Objective To investigate the …

Background Eosinophilic airway inflammation is observed in 10-30% of COPD subjects.
Whether increased eosinophils or impairment in their clearance by macrophages is …