Non-coding RNAs: update on mechanisms and therapeutic targets from the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart
Vast parts of mammalian genomes are actively transcribed, predominantly giving rise to non-
coding RNA (ncRNA) transcripts including microRNAs, long ncRNAs, and circular RNAs …
coding RNA (ncRNA) transcripts including microRNAs, long ncRNAs, and circular RNAs …
[HTML][HTML] The noncoding-RNA landscape in cardiovascular health and disease
V Di Mauro, M Barandalla-Sobrados… - Non-coding RNA …, 2018 - Elsevier
The cardiovascular system plays a pivotal role in regulating and maintaining homeostasis in
the human body. Therefore any alteration in regulatory networks that orchestrate heart …
the human body. Therefore any alteration in regulatory networks that orchestrate heart …
Non-coding RNAs as therapeutic targets and biomarkers in ischaemic heart disease
The adult heart is a complex, multicellular organ that is subjected to a series of regulatory
stimuli and circuits and has poor reparative potential. Despite progress in our understanding …
stimuli and circuits and has poor reparative potential. Despite progress in our understanding …
Non-coding RNAs: the “dark matter” of cardiovascular pathophysiology
Large-scale analyses of mammalian transcriptomes have identified a significant number of
different RNA molecules that are not translated into protein. In fact, the use of new …
different RNA molecules that are not translated into protein. In fact, the use of new …
Non-coding RNAs: emerging players in cardiomyocyte proliferation and cardiac regeneration
N Abbas, F Perbellini, T Thum - Basic Research in Cardiology, 2020 - Springer
Soon after birth, the regenerative capacity of the mammalian heart is lost, cardiomyocytes
withdraw from the cell cycle and demonstrate a minimal proliferation rate. Despite improved …
withdraw from the cell cycle and demonstrate a minimal proliferation rate. Despite improved …
Long non-coding RNAs: at the heart of cardiac dysfunction?
During the past decade numerous studies highlighted the importance of long non-coding
RNAs (lncRNAs) in orchestrating cardiovascular cell signaling. Classified only by a …
RNAs (lncRNAs) in orchestrating cardiovascular cell signaling. Classified only by a …
Non‐coding RNAs: key players in cardiac disease
Molecular mechanisms underlying heart failure (HF) are only partly understood. Non‐coding
RNAs (ncRNAs) have been reported to control function and signalling routes in the …
RNAs (ncRNAs) have been reported to control function and signalling routes in the …
Deciphering non-coding RNAs in cardiovascular health and disease
After being long considered as “junk” in the human genome, non-coding RNAs (ncRNAs)
currently represent one of the newest frontiers in cardiovascular disease (CVD) since they …
currently represent one of the newest frontiers in cardiovascular disease (CVD) since they …
Regulation of long non-coding RNAs and microRNAs in heart disease: insight into mechanisms and therapeutic approaches
L Collins, P Binder, H Chen, X Wang - Frontiers in Physiology, 2020 - frontiersin.org
Cardiovascular disease is the leading cause of mortality worldwide and there is an
increasing need to identify new therapeutic targets that could be used to prevent or treat …
increasing need to identify new therapeutic targets that could be used to prevent or treat …
Extracellular non-coding RNAs in cardiovascular diseases
Z Jiapaer, C Li, X Yang, L Sun, E Chatterjee, L Zhang… - Pharmaceutics, 2023 - mdpi.com
Cardiovascular diseases (CVDs) remain the world's leading cause of death despite the best
available healthcare and therapy. Emerging as a key mediator of intercellular and inter …
available healthcare and therapy. Emerging as a key mediator of intercellular and inter …