Background and purpose In order to increase local tumour control by radiotherapy without
increasing toxicity, it appears promising to harness functional imaging (FI) to guide dose to …

Radiation oncology has never been more integrated in the multidisciplinary treatment
approach of cancer than it is today. This results, in part, from pivotal prospective or …

Functional imaging could provide valuable information on the distribution of biological
factors that influence the outcome of radiation therapy. Tumour proliferation and cell density …

Over the past few years several automatic and semi-automatic PET segmentation methods
for target volume definition in radiotherapy have been proposed. The objective of this study …

Functional and molecular imaging of tumours have offered the possibility of redefining the
target in cancer therapy and individualising the treatment with a multidimensional approach …

This issue of Seminars in Nuclear Medicine deals with a watershed event in cancer
treatment—the combined use of functional and anatomical information to guide therapeutic …

In recent years, radiotherapy (RT) has been subject to a number of technological
innovations. Today, RT is extremely flexible, allowing irradiation of tumours with high doses …

There is increasing interest in how to incorporate functional and molecular information
obtained by noninvasive, three-dimensional tumor imaging into radiotherapy. The key …

Three-dimensional treatment planning systems allow the clinician to define tumor and
normal anatomy of computed tomograpy (CT) scans and project the result onto a digitally …

Purpose: To describe an emerging concept of high-precision radiotherapy, a modality
characterized by adaptation to patient and organ movements, which might occur between …