Acute inflammatory responses in the airways and peripheral blood after short-term exposure to diesel exhaust in healthy human volunteers

S Salvi, A Blomberg, B Rudell, F Kelly… - American journal of …, 1999 - atsjournals.org
Several epidemiologic studies have demonstrated a consistent association between levels
of particulate matter (PM) in the ambient air with increases in cardiovascular and respiratory …

Airway inflammation after controlled exposure to diesel exhaust particulates

JA NIGHTINGALE, R MAGGS, P Cullinan… - American journal of …, 2000 - atsjournals.org
Epidemiologic evidence suggests a link between morbidity and mortality and levels of
particulate matter in the atmosphere. We studied the inflammatory response to inhalation of …

[HTML][HTML] Effects of diesel exposure on lung function and inflammation biomarkers from airway and peripheral blood of healthy volunteers in a chamber study

Y Xu, L Barregard, J Nielsen, A Gudmundsson… - Particle and fibre …, 2013 - Springer
Background Exposure to diesel exhaust causes inflammatory responses. Previous
controlled exposure studies at a concentration of 300 μg/m 3 of diesel exhaust particles …

Different airway inflammatory responses in asthmatic and healthy humans exposed to diesel

N Stenfors, C Nordenhäll, SS Salvi… - European …, 2004 - Eur Respiratory Soc
Particulate matter (PM) pollution adversely affects the airways, with asthmatic subjects
thought to be especially sensitive. The authors hypothesised that exposure to diesel exhaust …

Proinflammatory doses of diesel exhaust in healthy subjects fail to elicit equivalent or augmented airway inflammation in subjects with asthma

AF Behndig, N Larsson, JL Brown, N Stenfors… - Thorax, 2011 - thorax.bmj.com
Background Exposure to traffic-derived air pollutants, particularly diesel emissions, has
been associated with adverse health effects, predominantly in individuals with pre-existing …

Acute exposure to diesel exhaust increases IL-8 and GRO-α production in healthy human airways

SS Salvi, C Nordenhall, A Blomberg… - American journal of …, 2000 - atsjournals.org
We have previously demonstrated that short-term exposure to diesel exhaust (DE) for 1 h
induced a marked leukocytic infiltration in the airways of healthy human volunteers involving …

Airway inflammation following exposure to diesel exhaust: a study of time kinetics using induced sputum

C Nordenhall, J Pourazar, A Blomberg… - European …, 2000 - Eur Respiratory Soc
The adverse health effects of particulate matter pollution are of increasing concern. In a
recent bronchoscopic study in healthy volunteers, pronounced airway inflammation was …

Airway antioxidant and inflammatory responses to diesel exhaust exposure in healthy humans

AF Behndig, IS Mudway, JL Brown… - European …, 2006 - Eur Respiratory Soc
Pulmonary cells exposed to diesel exhaust (DE) particles in vitro respond in a hierarchical
fashion with protective antioxidant responses predominating at low doses and inflammation …

Diesel exhaust enhances airway responsiveness in asthmatic subjects

C Nordenhäll, J Pourazar, MC Ledin… - European respiratory …, 2001 - Eur Respiratory Soc
Particulate matter (PM) pollution has been associated with negative health effects, including
exacerbations of asthma following exposure to PM peaks. The aim of the present study was …

Diesel exhaust particles and airway inflammation

AJ Ghio, CB Smith, MC Madden - Current opinion in pulmonary …, 2012 - journals.lww.com
Inflammation after diesel exhaust and DEP exposure is evident at higher concentrations
only; there appears to be a threshold dose for DEPs approximating 300 μg/m 3. The lack of a …