We previously reported that the intratracheal instillation of diesel exhaust particles enhances
allergic airway inflammation and hyperresponsiveness in mice. However, it is not known …

Outdoor air pollution exposure increases chronic obstructive pulmonary disease (COPD)
hospitalisations, and may contribute to COPD development. The mechanisms of harm, and …

Exposure to diesel exhaust particles (DEP) is an environmental and occupational health
concern. This review examines the cellular actions of the organic and the particulate …

Several plausible mechanisms have been proposed to explain the adverse health effects of
particulate matter (PM) in polluted ambient air [1]. To date, experimental support has been …

Several epidemiological studies have recently shown associations of increased premature
mortality rates with ambient paniculate air pollution. Diesel exhaust particles (DEP) may …

The effect of diesel exhaust particulate (DEP) exposure on innate, cellular and humoral
pulmonary immunity was studied using high-dose, acute-exposure rat, mouse, and cell …

There are at least three mechanisms by which alveolar macrophages play a critical role in
protecting the lung from bacterial or viral infections: production of inflammatory cytokines that …

Inhaled diesel exhaust particles (DEP) exert proinflammatory effects in the respiratory tract.
This effect is related to the particle content of redox cycling chemicals and is involved in the …

Epidemiologic studies demonstrate acute and serious adverse effects of particulate air
pollution on respiratory health, especially in people who are susceptible to bacterial …

Background Exposure to fine particulate air pollution is associated with increased
cardiovascular morbidity and mortality. We previously demonstrated that exposure to dilute …