New 6(17)-epoxylathyrane diterpene: aellinane from Euphorbia aellenii induces apoptosis via mitochondrial pathway in ovarian cancer cell line

F Nabatchian, A Moradi, M Aghaei… - Toxicology …, 2017 - Taylor & Francis
Euphorbia species have been used in traditional medicine in many countries for the
treatment of cancer. This article aims to evaluate the capability of a new lathyrane diterpene …

New Diterpene Compound from Euphorbia connate Boiss., 3,7,14,15-Tetraacetyl-5-Propanoyl-13(17)-Epoxy-8,10(18)-Myrsinadiene, Inhibits the Growth of Ovarian …

MH Abdolmohammadi, F Fallahian… - Nutrition and …, 2021 - Taylor & Francis
Ovarian cancer due to the difficulties in early clinical diagnosis and absence of successfull
treatment has poor prognosis and high mortality among all gynecological malignancies …

[HTML][HTML] Euphorbia factor L2 induces apoptosis in A549 cells through the mitochondrial pathway

M Lin, S Tang, C Zhang, H Chen, W Huang… - … pharmaceutica sinica B, 2017 - Elsevier
Euphorbia factor L2, a lathyrane diterpenoid isolated from caper euphorbia seed (the seeds
of Euphorbia lathyris L.), has been traditionally applied to treat cancer. This article focuses …

Liriodenine, an aporphine alkaloid from Enicosanthellum pulchrum, inhibits proliferation of human ovarian cancer cells through induction of apoptosis via the …

N Nordin, NA Majid, NM Hashim… - Drug design …, 2015 - Taylor & Francis
Enicosanthellum pulchrum is a tropical plant from Malaysia and belongs to the Annonaceae
family. This plant is rich in isoquinoline alkaloids. In the present study, liriodenine, an …

Structure identification of Euphorbia factor L3 and its induction of apoptosis through the mitochondrial pathway

JY Zhang, YJ Liang, HB Chen, LS Zheng, YJ Mi… - Molecules, 2011 - mdpi.com
In this article, we have focused on the structure identification of Euphorbia factor L3
belonging to the lathyrane diterpenoids isolated from Caper Euphorbia Seed. Its anticancer …

Diterpene pekinenal from euphorbia pekinensis radix induced IEC-6 cells apoptosis mediated by mitochondria and death receptors

F Yao, D Jiang, F Cheng, W Yao, P Chen, S Guo… - Toxicology in Vitro, 2019 - Elsevier
Pekinenal, a diterpenoid from the roots of Euphorbia pekinensis Rupr., can cause serious
intestinal toxicity. However, its toxic mechanism hasn't been comprehensively understood …

Eupalinolide J induces apoptosis, cell cycle arrest, mitochondrial membrane potential disruption and DNA damage in human prostate cancer cells

Z Wu, X Xu, L Dai, Y Wang, B Yang… - The Journal of …, 2020 - jstage.jst.go.jp
Eupalinolide J (EJ) is a new sesquiterpene lactone isolated from Eupatorium lindleyanum
DC. In the present study, we investigated the anti-cancer activity of EJ on cell proliferation in …

Emodin induces apoptosis of human cervical cancer hela cells via intrinsic mitochondrial and extrinsic death receptor pathway

W Yaoxian, Y Hui, Z Yunyan, L Yanqin, G Xin… - Cancer cell …, 2013 - Springer
Background Emodin is a natural anthraquinone derivative isolated from the Rheum
palmatum L. Aim: The aim of the present study was to investigate the effect of emodin on the …

Apoptosis induction by alantolactone in breast cancer MDA-MB-231 cells through reactive oxygen species-mediated mitochondrion-dependent pathway

L Cui, W Bu, J Song, L Feng, T Xu, D Liu… - Archives of pharmacal …, 2018 - Springer
Alantolactone is a sesquiterpene lactone isolated from Inula helenium L. Although
alantolactone possesses anti-inflammation and apoptosis-induction activities, the underlying …

[HTML][HTML] Jaceosidin induces apoptosis in human ovary cancer cells through mitochondrial pathway

W Lv, X Sheng, T Chen, Q Xu, X Xie - Journal of biomedicine and …, 2008 - ncbi.nlm.nih.gov
We examined the antiproliferation effect of Jaceosidin (4′, 5, 7-trihydroxy-3′, 6-
dimethoxyflavone) isolated from the herb of Artemisia vestita Wall on several human cancer …