“Sit back, observe, and wait.” Or is there a pharmacologic preventive treatment for cerebral aneurysms?

MM Valença - Neurosurgical review, 2013 - Springer
Intracranial aneurysms (IA) are a relatively frequent vascular abnormality. The prevailing
opinion is that cerebral aneurysmal disease is related to hemodynamic and genetic factors …

Treatment options of unruptured intracranial aneurysms

S Juvela - Stroke, 2004 - Am Heart Assoc
to 1.7%) was similar to that of smaller previously published patient series (1% to 3%) and
remained almost constant for decades. Significant risk factors for aneurysm rupture were …

Management of patients with unruptured intracranial aneurysms

GJE Rinkel - Current Opinion in Neurology, 2019 - journals.lww.com
In addition to risk factors used to predict absolute risks of rupture, also aneurysm irregularity
and aneurysm growth during follow-up are potential risk factors for rupture. To what extent …

[HTML][HTML] Unruptured intracranial aneurysms—pathogenesis and individualized management

N Etminan, A Dörfler, H Steinmetz - Deutsches Ärzteblatt …, 2020 - ncbi.nlm.nih.gov
Background About 2 million adults in Germany harbor an unruptured intracranial aneurysm
(IA). Rupture can lead to a life-threatening subarachnoid hemorrhage. If an IA is detected …

Current treatment strategies for intracranial aneurysms: an overview

J Zhao, H Lin, R Summers, M Yang, BG Cousins… - …, 2018 - journals.sagepub.com
Intracranial aneurysm is a leading cause of stroke. Its treatment has evolved over the past 2
decades. This review summarizes the treatment strategies for intracranial aneurysms from 3 …

[HTML][HTML] New pathophysiological considerations on cerebral aneurysms

KH Jung - Neurointervention, 2018 - synapse.koreamed.org
Cerebral aneurysm is a common cerebrovascular disease that is sometimes complicated by
rupture or an enlarged mass. We are now aggressively evaluating and managing …

Intracranial aneurysm: diagnostic monitoring, current interventional practices, and advances

JA Ellis, E Nossek, A Kronenburg, DJ Langer… - … Treatment Options in …, 2018 - Springer
Purpose of review Cerebral aneurysms are commonly diagnosed incidentally with non-
invasive neuro-imaging modalities (ie, brain MRA and/or head CTA). The first decision to be …

Candidate drugs for preventive treatment of unruptured intracranial aneurysms: A cross-sectional study

K Shimizu, H Imamura, S Tani, H Adachi, C Sakai… - PloS one, 2021 - journals.plos.org
Background and purpose Establishment of drug therapy to prevent rupture of unruptured
intracranial aneurysms (IAs) is needed. Previous human and animal studies have gradually …

Recommendations for the management of patients with unruptured intracranial aneurysms: a statement for healthcare professionals from the Stroke Council of the …

JB Bederson, IA Awad, DO Wiebers, D Piepgras… - Stroke, 2000 - Am Heart Assoc
Aneurysmal subarachnoid hemorrhage (SAH) has a 30-day mortality rate of 45%, with
approximately half the survivors sustaining irreversible brain damage. 1 On the basis of an …

ARISE I Consensus Review on the Management of Intracranial Aneurysms

SI Tjoumakaris, R Hanel, J Mocco, M Ali-Aziz Sultan… - Stroke, 2024 - Am Heart Assoc
BACKGROUND: Intracranial aneurysms (IAs) remain a challenging neurological diagnosis
associated with significant morbidity and mortality. There is a plethora of microsurgical and …