Genetic studies traditionally focus on DNA as the molecule that passes information on from
parents to their offspring. Changes in the DNA code alter heritable information and can more …

It is known that information that is not contained in the DNA sequence—epigenetic
information—can be inherited from the parent to the offspring. However, many questions …

Reproductive disease and fertility issues have dramatically increased in the human
population over the last several decades, suggesting environmental impacts. Epigenetics …

Environmental factors can induce epigenetic alterations in the germ cells that can potentially
be transmitted transgenerationally. This non-genetic form of inheritance is termed epigenetic …

Epigenetic mechanisms involving DNA methylation, histone modification, histone variants
and nucleosome positioning, and noncoding RNAs regulate cell-, tissue-, and …

DNA methylation is one of the epigenetic and hereditary mechanisms regulating genetic
expression in mammalian cells. In this review, we propose how certain natural agents …

Parental effects are a major source of phenotypic plasticity. Moreover, there is evidence from
studies with a wide range of species that the relevant parental signals are influenced by the …

Literature on maternal exposures and the risk of epigenetic changes or diseases in the
offspring is growing. Paternal contributions are often not considered. However, some animal …

Parental effects are a major source of phenotypic plasticity and may influence offspring
phenotype in concert with environmental demands. Studies of “environmental epigenetics” …

The ability of an environmental factor or toxicant to promote a phenotype or disease state not
only in the individual exposed, but also in subsequent progeny for multiple generations, is …