Neuropeptide Y receptor in pig spleen: binding characteristics, reduction of cyclic AMP formation and calcium antagonist inhibition of vasoconstriction

JM Lundberg, A Hemsén, O Larsson, A Rudehill… - European journal of …, 1988 - Elsevier
Specific, high-affinity binding sites for 125 I-porcine neuropeptide Y (NPY) were
demonstrated in membranes from the pig spleen. The equilibrium dissociation constant (KD) …

Dissociation of potentiation of Leu31 Pro34 neuropeptide Y on adrenergic and purinergic transmission in isolated canine splenic artery

XP Yang, S Chiba - The Japanese Journal of Pharmacology, 2000 - jstage.jst.go.jp
抄録 The present study observed the effects of an activation of neuropeptide Y (NPY) Y 1
receptors on adrenergic and purinergic components of double− peaked vasoconstrictor …

Pharmacology of noradrenaline and neuropeptide tyrosine (NPY)‐mediated sympathetic cotransmission

JM Lundberg, A Franco‐Cereceda… - Fundamental & …, 1990 - Wiley Online Library
Pharmacological and physiological aspects for neuropeptide Y (NPY) and noradrenaline
(NA) cotransmission have been studied in the peripheral sympathetic nervous control of …

NPY Y2 receptor agonist, N-acetyl [Leu28, Leu31] NPY24–36, reduces renal vasoconstrictor activity in anaesthetised dogs

DA Mahns, C Kelly, DI McCloskey, EK Potter - Journal of the autonomic …, 1999 - Elsevier
The actions of neuropeptide Y (NPY) at the autonomic neuroeffector junction have been
attributed to two main receptor subtypes. At NPY Y1 receptors, located postsynaptically, NPY …

Neuropeptide Y induces and modulates vasoconstriction in intracranial and peripheral vessels of animals and man

JH Hanko, K Törnebrandt, JE Hardebo… - Journal of Autonomic …, 1986 - Wiley Online Library
1 Neuropeptide Y (NPY) has recently been reported to coexist with noradrenaline (NA) in
central as well as peripheral noradrenergic nerves. NPY‐containing nerve fibres are …

Neuropeptide Y-and alpha-adrenergic receptors in pig spleen: localization, binding characteristics, cyclic AMP effects and functional responses in control and …

JM Lundberg, A Hemsen, A Rudehill, A Härfstrand… - Neuroscience, 1988 - Elsevier
The localization of neuropeptide Y binding sites in the pig spleen, as revealed by [125 I]
Bolton-Hunter-labelled porcine neuropeptide Y and alpha 1-adrenergic receptor binding …

Time‐dependent effects of ischaemia on neuropeptide Y mechanisms in pig renal vascular control in vivo

RE Malmstrøm, JM Lundberg - Acta physiologica scandinavica, 1997 - Wiley Online Library
We have investigated the effects of ischaemia on neuropeptide Y (NPY) mechanisms
involved in sympathetic vascular control of the pig kidney in vivo. Reperfusion after 2 h of …

Cardiac vagal action and plasma levels of neuropeptide Y following intravenous injection in the dog

EK Potter - Neuroscience letters, 1987 - Elsevier
Neuropeptide Y (NPY) is a 36-amino acid peptide found co-localised with catecholamines in
many sympathetic postganglionic nerves. Intravenous injection of NPY (6–10 nM/kg) in dogs …

α2-Adrenoceptor-mediated inhibition of nerve stimulation-evoked release of neuropeptide Y (NPY)-like immunoreactivity in the pithed guinea-pig

C Dahlöf, P Dahlöf, JM Lundberg - European journal of pharmacology, 1986 - Elsevier
Clonidine (10 μg× kg− 1) reduced by almost 50% the increase in plasma neuropeptide
(NPY)-like immunoreactivity (-LI) induced by preganglionic nerve stimulation at 8 Hz. This …

Cardiovascular effects and modulation of noradrenergic neurotransmission following central and peripheral administration of neuropeptide Y

TC Westfall, J Martin, X Chen, A Ciarleglio… - Synapse, 1988 - Wiley Online Library
Experiments have been conducted to evaluate the effect of neuropeptide Y (NPY)
administered at three distinct levels of the nervous system:(1) the posterior hypothalamic …