Role of bile acids and their receptors in gastrointestinal and hepatic pathophysiology
CD Fuchs, M Trauner - Nature reviews Gastroenterology & hepatology, 2022 - nature.com
Bile acids (BAs) can regulate their own metabolism and transport as well as other key
aspects of metabolic homeostasis via dedicated (nuclear and G protein-coupled) receptors …
aspects of metabolic homeostasis via dedicated (nuclear and G protein-coupled) receptors …
Molecular physiology of bile acid signaling in health, disease, and aging
A Perino, H Demagny… - Physiological …, 2021 - journals.physiology.org
Over the past two decades, bile acids (BAs) have become established as important
signaling molecules that enable fine-tuned inter-tissue communication from the liver, their …
signaling molecules that enable fine-tuned inter-tissue communication from the liver, their …
Bile acid signaling in the regulation of whole body metabolic and immunological homeostasis
W Jia, Y Li, KCP Cheung, X Zheng - Science China Life Sciences, 2024 - Springer
Bile acids (BAs) play a crucial role in nutrient absorption and act as key regulators of lipid
and glucose metabolism and immune homeostasis. Through the enterohepatic circulation …
and glucose metabolism and immune homeostasis. Through the enterohepatic circulation …
Bile acids in glucose metabolism in health and disease
H Shapiro, AA Kolodziejczyk, D Halstuch… - Journal of Experimental …, 2018 - rupress.org
Bile acids (BAs) are cholesterol-derived metabolites that facilitate the intestinal absorption
and transport of dietary lipids. Recently, BAs also emerged as pivotal signaling molecules …
and transport of dietary lipids. Recently, BAs also emerged as pivotal signaling molecules …
Bile acids as regulators of hepatic lipid and glucose metabolism
Besides their well-established roles in dietary lipid absorption and cholesterol homeostasis,
bile acids (BA) also act as metabolically active signaling molecules. The flux of reabsorbed …
bile acids (BA) also act as metabolically active signaling molecules. The flux of reabsorbed …
therapeutic aspects of bile acid signalling in the gut‐liver axis
B Simbrunner, M Trauner… - Alimentary Pharmacology …, 2021 - Wiley Online Library
Background Bile acids are important endocrine modulators of intestinal and hepatic
signalling cascades orchestrating critical pathophysiological processes in various liver …
signalling cascades orchestrating critical pathophysiological processes in various liver …
Endocrine functions of bile acids
Bile acids (BAs), a group of structurally diverse molecules that are primarily synthesized in
the liver from cholesterol, are the chief components of bile. Besides their well‐established …
the liver from cholesterol, are the chief components of bile. Besides their well‐established …
Bile acid homeostasis paradigm and its connotation with cholestatic liver diseases
Highlights•Cholestatic liver diseases and bile acid homeostasis are closely
connected.•Numerous signaling molecules are associated with bile acid transporters, tight …
connected.•Numerous signaling molecules are associated with bile acid transporters, tight …
[HTML][HTML] Intestinal bile acid physiology and pathophysiology
O Martínez-Augustin, FS de Medina - World journal of …, 2008 - ncbi.nlm.nih.gov
Bile acids (BAs) have a long established role in fat digestion in the intestine by acting as
tensioactives, due to their amphipathic characteristics. BAs are reabsorbed very efficiently by …
tensioactives, due to their amphipathic characteristics. BAs are reabsorbed very efficiently by …
[HTML][HTML] Bile acid transporters and regulatory nuclear receptors in the liver and beyond
E Halilbasic, T Claudel, M Trauner - Journal of hepatology, 2013 - Elsevier
Bile acid (BA) transporters are critical for maintenance of the enterohepatic BA circulation
where BAs exert their multiple physiological functions including stimulation of bile flow …
where BAs exert their multiple physiological functions including stimulation of bile flow …