Heparan sulfate (HS) proteoglycans (PGs) are ubiquitously expressed on cell surfaces and
in the extracellular matrix of most animal tissues, having essential functions in development …

Heparan sulfate (HS) proteoglycans at cell surfaces and in the extracellular matrix of most
animal tissues are essential in development and homeostasis, and variously implicated in …

Nearly all vertebrate cells have been shown to express heparan sulfate proteoglycans
(HSPGs) at the cell surface. The HSPGs bind to many secreted signaling proteins, including …

The heparan sulfates (HS) are hypervariable linear polysaccharides that act as membrane
co-receptors for growth factors, chemokines, and extracellular matrix proteins. In most …

The heparan sulfates are a family of cell-surface and matrix polysaccharides with an
incredible degree of structural diversity that are distributed widely in virtually all metazoan …

Heparin and the related glycosaminoglycan, heparan sulfate, bind a myriad of proteins. The
structural diversity of heparin and heparan sulfates is enormous, but differences in the …

Large numbers of proteins in animal tissues occur immobilized in the extracellular space, at
cell surfaces or in the extracellular matrix. Some are anchored through interactions with …

J. Clin. Invest. 108: 175–180 (2001). DOI: 10.1172/JCI200113561. a molecular design in
which clusters of N-and O-sulfated sugar residues (red or green in Figure 1) are separated …

Heparan sulfate (HS), is a proteoglycan (PG) found both in the extracellular matrix and on
cell surface. It may represent one of the most biologically important glycoconjugates, playing …

The sulfated glycosaminoglycans, heparan sulfate and heparin, are increasingly implicated
in cell‐biological processes such as cytokine action, cell adhesion, and regulation of …