Multiple sclerosis and CCSVI: a population-based case control study

F Patti, A Nicoletti, C Leone, S Messina, E D'Amico… - 2012 - journals.plos.org
Background Chronic cerebrospinal venous insufficiency (CCSVI) has been associated to
multiple sclerosis (MS). Objective To evaluate the possible association between CCSVI and …

Chronic cerebrospinal venous insufficiency and the doubtful promise of an endovascular treatment for multiple sclerosis

H Dorne, OO Zaidat, D Fiorella, J Hirsch… - Journal of …, 2010 - jnis.bmj.com
As neurointerventionalists interested in interventional treatment of neurological disorders, it
is time to take a thorough and objective look at CCSVI. This commentary will examine the …

CCSVI and MS: no meaning, no fact

C Baracchini, M Atzori, P Gallo - Neurological Sciences, 2013 - Springer
A condition called “chronic cerebrospinal venous insufficiency”(CCSVI) has been postulated
to play a role in the pathogenesis of multiple sclerosis (MS). This hypothesis implies that a …

Chronic cerebrospinal venous insufficiency and multiple sclerosis: history and background

MD Dake - Techniques in vascular and interventional radiology, 2012 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system
(CNS) most commonly characterized by focal areas of myelin destruction, inflammation and …

What went wrong? The flawed concept of cerebrospinal venous insufficiency

JM Valdueza, F Doepp, SJ Schreiber… - Journal of Cerebral …, 2013 - journals.sagepub.com
In 2006, Zamboni reintroduced the concept that chronic impaired venous outflow of the
central nervous system is associated with multiple sclerosis (MS), coining the term of chronic …

Proposed chronic cerebrospinal venous insufficiency criteria do not predict multiple sclerosis risk or severity

D Centonze, R Floris, M Stefanini, S Rossi… - Annals of …, 2011 - Wiley Online Library
Objective: It is still unclear whether chronic cerebrospinal venous insufficiency (CCSVI) is
associated with multiple sclerosis (MS), because substantial methodological differences …

Chronic cerebrospinal venous insufficiency in multiple sclerosis: diagnostic, pathogenetic, clinical and treatment perspectives

R Zivadinov, M Ramanathan, K Dolic… - Expert review of …, 2011 - Taylor & Francis
Chronic cerebrospinal venous insufficiency (CCSVI) was recently described in multiple
sclerosis patients. CCSVI is characterized by impaired brain venous drainage due to outflow …

Editorial [Hot Topic: New Avenues of Research on Multiple Sclerosis from the Perspective of Chronic Cerebrospinal Venous Insufficiency Paradigm (Guest Editor …

M Simka - Reviews on Recent Clinical Trials, 2012 - ingentaconnect.com
Multiple sclerosis (MS) is a chronic and debilitating neurological disease characterized by
multifocal areas of inflammation, demyelination and neurodegeneration within the brain and …

Percutaneous transluminal angioplasty for treatment of chronic cerebrospinal venous insufficiency in people with multiple sclerosis: a summary of a Cochrane …

EJ van Zuuren, Z Fedorowicz, E Pucci… - Journal of Neurology …, 2014 - jnnp.bmj.com
Background It has been recently hypothesised that chronic cerebrospinal venous
insufficiency (CCSVI) may be an important factor in the pathogenesis of multiple sclerosis …

Cerebrospinal venous insufficiency and multiple sclerosis: investigating the truth

O Khan - Multiple Sclerosis Journal, 2011 - journals.sagepub.com
The hypothesis that extra-cranial venous flow abnormalities leading to a stagnant venous
return contribute to the pathogenesis of multiple sclerosis (MS) has generated passionate …