[HTML][HTML] Multicontrast photoacoustic in vivo imaging using near-infrared fluorescent proteins

A Krumholz, DM Shcherbakova, J Xia, LV Wang… - Scientific reports, 2014 - nature.com
Non-invasive imaging of biological processes in vivo is invaluable in advancing biology.
Photoacoustic tomography is a scalable imaging technique that provides higher resolution …

Multiscale photoacoustic tomography of a genetically encoded near‐infrared FRET biosensor

L Li, HC Hsu, VV Verkhusha, LV Wang… - Advanced …, 2021 - Wiley Online Library
Photoacoustic tomography (PAT) with genetically encoded near‐infrared probes enables
visualization of specific cell populations in vivo at high resolution deeply in biological …

[HTML][HTML] Dual-wavelength 3D photoacoustic imaging of mammalian cells using a photoswitchable phytochrome reporter protein

J Märk, H Dortay, A Wagener, E Zhang… - Communications …, 2018 - nature.com
Photoacoustic imaging has been shown to provide high-resolution images of genetically
labelled cells at depths that are inaccessible to optical microscopy. While the detection of …

[HTML][HTML] Deep in vivo photoacoustic imaging of mammalian tissues using a tyrosinase-based genetic reporter

AP Jathoul, J Laufer, O Ogunlade, B Treeby, B Cox… - Nature …, 2015 - nature.com
Photoacoustic imaging allows absorption-based high-resolution spectroscopic in vivo
imaging at a depth beyond that of optical microscopy. Until recently, photoacoustic imaging …

Photoacoustic imaging

L Lin, LV Wang - Optical Imaging in Human Disease and Biological …, 2021 - Springer
Photoacoustic imaging (PAI) is an emerging imaging modality that shows great potential for
preclinical research and clinical practice. As a hybrid technique, PAI uniquely combines the …

Looking deep inside tissue with photoacoustic molecular probes: a review

X Hui, MOA Malik, M Pramanik - Journal of biomedical optics, 2022 - spiedigitallibrary.org
Significance: Deep tissue noninvasive high-resolution imaging with light is challenging due
to the high degree of light absorption and scattering in biological tissue. Photoacoustic …

Multispectral opto-acoustic tomography of deep-seated fluorescent proteins in vivo

D Razansky, M Distel, C Vinegoni, R Ma, N Perrimon… - Nature …, 2009 - nature.com
Fluorescent proteins have become essential reporter molecules for studying life at the
cellular and sub-cellular level, re-defining the ways in which we investigate biology …

Functional photoacoustic microscopy for high-resolution and noninvasive in vivo imaging

HF Zhang, K Maslov, G Stoica, LV Wang - Nature biotechnology, 2006 - nature.com
Although optical absorption is strongly associated with the physiological status of biological
tissue, existing high-resolution optical imaging modalities, including confocal microscopy …

Photoacoustic molecular imaging: from multiscale biomedical applications towards early-stage theranostics

Y Liu, L Nie, X Chen - Trends in biotechnology, 2016 - cell.com
Photoacoustic imaging (PAI) has ushered in a new era of observational biotechnology and
has facilitated the exploration of fundamental biological mechanisms and clinical …

Deep‐tissue photoacoustic tomography of a genetically encoded near‐infrared fluorescent probe

GS Filonov, A Krumholz, J Xia, J Yao… - Angewandte Chemie …, 2012 - Wiley Online Library
Skin‐deep: The combination of a near‐infrared fluorescent protein (iRFP) and deep‐tissue
photoacoustic tomography clearly demonstrates the superiority of iRFP over other …