Replicating the naturalistic biomechanical milieu of cells is a primary requisite to uncover the
fundamental life processes. The native milieu is significantly not replicated in the two …

Vibrational spectroscopy is increasingly used for the rapid and non-destructive imaging of
environmental and medical samples. Both Raman and Fourier-transform infrared (FT-IR) …

Laser tweezers Raman spectroscopy (LTRS) is a variation of micro-Raman spectroscopy
that is used to analyze single cells and biological particles suspended in an aqueous …

For the first time, the ability of in situ Raman and Near Infrared (NIR) spectroscopies to
predict in real-time the concentration of viable Chinese Hamster Ovary (CHO) cells, glucose …

There are many techniques that allow in vitro interactions among cells and their environment
to be monitored, including molecular, biochemical and immunochemical techniques …

The rapid development of three‐dimensional (3D) culture systems and engineered cell‐
based tissue models gave rise to an increasing need of new techniques, allowing the …

Chinese hamster ovary (CHO) cells are widely utilized in the production of antibody drugs.
To ensure the production of large quantities of antibodies that meet the required …

Microscopy techniques are widely used in life sciences to study cells and tissues.
Fluorescence microscopy, for example, is a very common method in many laboratories …

The FDA's process analytical technology initiative encourages drug manufacturers to apply
innovative ideas to better understand their processes. There are many challenges to …

A review with 105 references that analyzes the emerging research area of 3D cell culture in
microfluidic platforms with integrated detection schemes. Over the last several decades a …