Prevalence of integrase strand transfer inhibitors (INSTI) resistance mutations in Taiwan

SY Chang, PH Lin, CL Cheng, MY Chen, HY Sun… - Scientific reports, 2016 - nature.com
Antiretroviral therapy containing an integrase strand transfer inhibitor (INSTI) plus two NRTIs
has become the recommended treatment for antiretroviral-naive HIV-1-infected patients in …

Detection of drug resistance-associated mutations in human immunodeficiency virus type 1 integrase derived from drug-naive individuals in Surabaya, Indonesia

T Kotaki, SQ Khairunisa, SD Sukartiningrum… - AIDS Research and …, 2014 - liebertpub.com
Although human immunodeficiency virus type 1 (HIV-1) infection causes serious health
problems in Indonesia, information in regard to drug resistance is limited. We performed a …

Prevalence of integrase strand transfer inhibitor (INSTI) resistance in people living with HIV and virological failure

HC Tsai, IT Chen, HM Chang, YT Tseng… - Journal of the Chinese … - journals.lww.com
Background: This study aims to delineate the resistance profiles to integrase strand transfer
inhibitors (INSTIs) among patients in southern Taiwan who have experienced antiretroviral …

Low frequency of integrase inhibitor resistance mutations among therapy-naive HIV patients in southeast China

J Lai, Y Liu, X Han, A Huang, J Lin, W Ao… - Drug Design …, 2021 - Taylor & Francis
Background With the widespread use of integrase strand transfer inhibitors (INSTIs) in the
clinical setting, transmission of INSTIs-resistance mutations may increase. Data regarding …

Integrase variability and susceptibility to HIV integrase inhibitors: impact of subtypes, antiretroviral experience and duration of HIV infection

C Garrido, AM Geretti, N Zahonero… - Journal of …, 2010 - academic.oup.com
Background Little is known about the extent and predictors of polymorphisms potentially
influencing the susceptibility to HIV integrase inhibitors (INIs). Methods Genetic sequences …

Specific HIV-1 integrase polymorphisms change their prevalence in untreated versus antiretroviral-treated HIV-1-infected patients, all naive to integrase inhibitors

F Ceccherini-Silberstein, I Malet… - Journal of …, 2010 - academic.oup.com
Objectives To define whether the prevalence of mutations associated with integrase inhibitor
(INI) resistance is different in untreated versus antiretroviral-treated HIV-1-infected …

Integrase inhibitor (INI) genotypic resistance in treatment-naive and raltegravir-experienced patients infected with diverse HIV-1 clades

T Doyle, DT Dunn… - Journal of …, 2015 - academic.oup.com
Objectives The aim of this study was to characterize the prevalence and patterns of
genotypic integrase inhibitor (INI) resistance in relation to HIV-1 clade. Methods The cohort …

[PDF][PDF] HIV-1 Subtype C Drug Resistance Mutations in Heavily Treated Patients Failing Integrase Strand Transfer Inhibitor-Based Regimens in Botswana. Viruses …

KK Seatla, D Maruapula, WT Choga… - DOI: https://doi. org …, 2021 - academia.edu
There are limited real-world mutational and virological outcomes data of
treatmentexperienced persons diagnosed with HIV-1 subtype C (HIV-1 C) who are failing …

Integrase strand transfer inhibitor resistance mutations in antiretroviral therapy-naive and treatment-experienced HIV patients in South Korea

W Jeong, IY Jung, H Choi, JH Kim, H Seong… - AIDS research and …, 2019 - liebertpub.com
Updated guidelines for the treatment of antiretroviral therapy (ART)-negative patients with
HIV recommend integrase strand transfer inhibitor (INSTI)-based regimens. HIV patients are …

Surveillance of HIV-1 transmitted integrase strand transfer inhibitor resistance in the UK

JL Mbisa, J Ledesma, P Kirwan… - Journal of …, 2020 - academic.oup.com
Background HIV treatment guidelines have traditionally recommended that all HIV-positive
individuals are tested for evidence of drug resistance prior to starting ART. Testing for …