Biological functions and applications of LncRNAs in the regulation of the extracellular matrix in osteoarthritis

D Shi, Y Mei, W Hao, J Li, S Liu, X Lin - Frontiers in Cell and …, 2024 - frontiersin.org
Osteoarthritis (OA) is a major cause of disability, characterized by chronic pain, irreversible
destruction, and loss of function of the articular cartilage. The integrity and arrangement of …

[HTML][HTML] The emerging role of lncRNAs in chondrocytes from osteoarthritis patients

J Tu, W Huang, W Zhang, J Mei, C Zhu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Long non-coding RNAs (lncRNAs) play important roles in many physiological and
pathological processes, including osteoarthritis (OA). Recent studies have demonstrated …

lncRNAs: function and mechanism in cartilage development, degeneration, and regeneration

J Zhu, W Yu, Y Wang, K Xia, Y Huang, A Xu… - Stem cell research & …, 2019 - Springer
With the increasing incidence of cartilage-related diseases such as osteoarthritis (OA) and
intervertebral disc degeneration (IDD), heavier financial and social burdens need to be …

[HTML][HTML] Emerging roles of long noncoding RNA in chondrogenesis, osteogenesis, and osteoarthritis

H Sun, G Peng, X Ning, J Wang, H Yang… - American journal of …, 2019 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is the most prevalent age-related debilitating joint disease, and is
characterized primarily by articular cartilage degradation and subchondral bone lesions. It is …

[HTML][HTML] Long noncoding RNAs: a new regulatory code in osteoarthritis

X Cen, XQ Huang, WT Sun, Q Liu… - American journal of …, 2017 - ncbi.nlm.nih.gov
It is reported that long noncoding RNAs (lncRNAs) were expressed aberrantly in cartilage of
osteoarthritis (OA). Current evidence indicates that lncRNAs not only serve as positive or …

Advances in Research on the Regulatory Roles of lncRNAs in Osteoarthritic Cartilage

J Wu, Z Zhang, X Ma, X Liu - Biomolecules, 2023 - mdpi.com
Osteoarthritis (OA) is the most common degenerative bone and joint disease that can lead to
disability and severely affect the quality of life of patients. However, its etiology and …

Long noncoding RNAs in osteoarthritis

J Lu, Z Deng, Y Li, G Lei - Joint Bone Spine, 2017 - Elsevier
Osteoarthritis (OA) is the most common form of arthritis that may affect all joint tissues.
Unfortunately, the pathogenesis of OA is not fully understood yet and it cannot be cured …

The role and function of long non-coding RNAs in osteoarthritis

M Abbasifard, Z Kamiab… - … and molecular pathology, 2020 - Elsevier
Osteoarthiritis (OA) is the most prevalent disease of articulating joints in human that
frequently results in joint pain, movement limitations, inflammation, and progressive …

The function of lncRNAs in the pathogenesis of osteoarthritis

CP He, XC Jiang, C Chen, HB Zhang… - Bone & joint …, 2021 - boneandjoint.org.uk
Osteoarthritis (OA), one of the most common motor system disorders, is a degenerative
disease involving progressive joint destruction caused by a variety of factors. At present, OA …

[HTML][HTML] MicroRNAs and long non-coding RNAs in cartilage homeostasis and osteoarthritis

J Gu, W Rao, S Huo, T Fan, M Qiu, H Zhu… - Frontiers in Cell and …, 2022 - frontiersin.org
During the last decade, osteoarthritis (OA) has become one of the most prevalent
musculoskeletal diseases worldwide. OA is characterized by progressive loss of articular …