Responses of cerebral arteries and arterioles to acute hypotension and hypertension

HA Kontos, EP Wei, RM Navari… - American Journal …, 1978 - journals.physiology.org
The responses of cerebral precapillary vessels to changes in arterial blood pressure were
studied in anesthetized cats equipped with cranial windows for the direct observation of the …

Effects of acutely induced hypertension in cats on pial arteriolar caliber, local cerebral blood flow, and the blood-brain barrier.

ET MacKenzie, S Strandgaard, DI Graham… - Circulation …, 1976 - Am Heart Assoc
Acute hypertension was induced in 19 anesthetized cats by the intravenous administration
of angiotensin. The caliber of pial arteries was measured by a television image-splitting …

Effects of sympathetic nerves on cerebral vessels during acute, moderate increases in arterial pressure in dogs and cats.

DW Busija, DD Heistad, ML Marcus - Circulation Research, 1980 - Am Heart Assoc
SUMMARY We studied:(1) the effects of an abrupt, moderate increase in arterial pressure on
total and regional cerebral blood flow (CBF) and (2) whether sympathetic stimulation …

Mechanism of cerebral arteriolar abnormalities after acute hypertension

HA Kontos, EP Wei, WD Dietrich… - American Journal …, 1981 - journals.physiology.org
Acute severe hypertension induced by intravenous norepinephrine or angiotensin in
anesthetized cats equipped with a cranial window caused prolonged arteriolar vasodilation …

Role of large arteries in regulation of cerebral blood flow in dogs

DD Heistad, ML Marcus… - The Journal of clinical …, 1978 - Am Soc Clin Investig
Previous studies have demonstrated a significant pressure gradient from carotid artery to
pial or middle cerebral arteries. This pressure gradient suggests that large cerebral arteries …

Dependence of pial arteriolar response to hypercapnia on vessel size

EP Wei, HA Kontos… - American Journal of …, 1980 - journals.physiology.org
The responses of pial arterioles to changes in PaCOCO2 were studied in anesthetized cats
equipped with cranial windows for the observation of the pial microcirculation. The …

Mechanics of cerebral arterioles in hypertensive rats.

GL Baumbach, PB Dobrin, MN Hart… - Circulation …, 1988 - Am Heart Assoc
Chronic hypertension is associated with hypertrophy of cerebral blood vessels. Previous
studies of the mechanical properties of cerebral vessels in chronic hypertension have …

Effects of local reduction in pressure on distensibility and composition of cerebral arterioles.

GL Baumbach, JE Siems, DD Heistad - Circulation research, 1991 - Am Heart Assoc
This study examined effects of local reductions in mean and pulse pressures on cerebral
arterioles in normotensive Wistar-Kyoto rats (WKY) and stroke-prone spontaneously …

Regulation of large cerebral arteries and cerebral microvascular pressure.

FM Faraci, DD Heistad - Circulation research, 1990 - Am Heart Assoc
Resistance of large arteries appears to be greater in the cerebral circulation than in other
vascular beds. Large arteries contribute importantly to total cerebral vascular resistance and …

Microvascular adaptation in the cerebral cortex of adult spontaneously hypertensive rats.

SL Harper, HG Bohlen - Hypertension, 1984 - Am Heart Assoc
The purpose of this study was to determine the microvascular characteristics that cause
cerebral cortical blood flow autoregulation to shift to a higher range of arterial pressures …