Stem cells in the kidney. The kidney is derived from the ureteric bud and the
metanephrogenic mesenchyme, and these two progenitor cells differentiate into more than …

A tissue stem cell should exhibit long-term self-renewal, clonogenicity and a capacity to
differentiate into the tissue of origin. Such a postnatal renal stem cell has not been formally …

The therapeutic potential of adult stem cells in the treatment of chronic degenerative
diseases has becoming increasingly evident over the last few years. Significant attention is …

Many adult organs contain stem cells, which are pluripotent and are involved in organ
maintenance and repair after injury. In situ, these cells often have a low cycling rate and …

Global glomerulosclerosis with loss of podocytes in humans is typical of end-stage renal
pathology. Although mature podocytes are highly differentiated and nondividing, converging …

Renal epithelial cells derive from either cells of the metanephric mesenchyme or ureteric
bud cells, but the origin of other renal cells is unclear. To test whether metanephric …

Increasing interest in the potential of adult stem cells in regenerative medicine has led to
numerous studies focused on the identification of endogenous renal stem cells within the …

Renal cells are used in basic research, disease models, tissue engineering, drug screening,
and in vitro toxicology. In order to provide a reliable source of human renal cells, we …

In humans, renal resident stem cells were identified within the interstitium, the tubular cells,
and the Bowman's capsule. The aim of the present study was to investigate whether …

Mesenchymal cells have been isolated from embryos and multiple adult organs where they
may differentiate into various connective tissue cell types and provide paracrine support for …