Background Despite extensive efforts to develop and refine intervention packages, complex
interventions often fail to produce the desired health impacts in full-scale evaluations. A …

Background Complex interventions—those that contain several interacting components—to
improve clinical outcomes and population health are growing because of the increasing …

Background Pragmatic and adaptive trial designs are increasingly used in quality
improvement (QI) interventions to provide the strongest evidence for effective …

Background Quick scaling-up of innovative and promising interventions in health systems of
low and middle-income countries to rapidly achieve population level benefits is a key …

Commentary to have had an effect, such as aseptic management of central vascular lines
and restrictive prescribing of antibiotics, were already standard practice in most centres …

At the outset of designing an intervention, investigators need to begin thinking about the
translation of their intervention into real-world practice settings if findings from their research …

Many interventions that are delivered within public health services have little evidence of
effect. Evaluating interventions that are being delivered as a part of usual practice offers …

In an effort aimed at improving outcomes, obstetric teams have enacted comprehensive care
bundles and other clinical tools. Yet, these practices have had limited degrees of success on …

Purpose This article uses an evaluation of New Heights, a school-based program for
pregnant and parenting teens in the District of Columbia Public Schools, to illustrate how …

The burden of maternal and infant deaths falls disproportionately on low income countries
(LICs) and lower middle income countries (LMCs1) and among the poorest within these …