Inhibition of the renin-angiotensin-aldosterone system (RAAS) either via ACE-inhibition, or
more recently via the use of angiotensin II receptor antagonists (AIIAs), has become an …

More than a century of research on the renin-angiotensin system (RAS) has uncovered the
widespread involvement of angiotensin II (Ang II) in the pathophysiology of cardiovascular …

A collective century of discoveries establishes the importance of the renin angiotensin
aldosterone system in maintaining blood pressure, fluid volume and electrolyte homeostasis …

A progressive chain of pathophysiological events links cardiovascular risk factors to clinical
manifestations of disease and life-threatening cardiovascular events. This chain–the …

The unraveling of the role of the renin-angiotensin system (RAS) in health and disease is an
example of how basic and applied scientists can decipher a complex biological system to …

The renin-angiotensin system (RAS) plays a pivotal role in the progression of some forms of
hypertension and cardiovascular disease. The development of angiotensin-converting …

Angiotensin II plays a central role in the regulation of systemic arterial pressure through its
systemic synthesis via the renin-angiotensin-aldosterone cascade. It acts directly on …

The renin-angiotensin system is central to the pathophysiology of a number of
cardiovascular disorders. Most obviously this is so with renin secreting tumours, but the …

The renin-angiotensin-aldosterone system (RAAS) plays an important role in blood pressure
control and volume homeostasis. Inappropriate activation of the RAAS has been implicated …

Scientific evidence currently available supports the concept that renin-angiotensin blockade
with angiotensin converting enzyme inhibitors as a first-line treatment exhibits in arterial …