[HTML][HTML] Sex and hormonal status influence the anxiolytic-like effect of oxytocin in mice

KE Nisbett, LA Gonzalez, M Teruel, CS Carter… - Neurobiology of …, 2023 - Elsevier
Anxiety and depression are highly prevalent psychiatric disorders, affecting approximately
18% of the United States population. Evidence indicates that central oxytocin mediates …

Oxytocin enhances resting-state connectivity between amygdala and medial frontal cortex

CS Sripada, KL Phan, I Labuschagne… - International Journal …, 2013 - academic.oup.com
The neuropeptide oxytocin (OXT) plays an important role in complex socio-affective
behaviours such as affiliation, attachment, stress and anxiety. Previous studies have focused …

Oxytocin influences processing of socially relevant cues in the ventral tegmental area of the human brain

SE Groppe, A Gossen, L Rademacher, A Hahn… - Biological …, 2013 - Elsevier
Background Evidence accumulates that the neuropeptide oxytocin plays an important role in
mediating social interaction among humans and that a dysfunction in oxytocin-modulated …

Molecular basis of oxytocin receptor signalling in the brain: what we know and what we need to know

M Busnelli, B Chini - Behavioral pharmacology of neuropeptides: Oxytocin, 2018 - Springer
Oxytocin (OT), a hypothalamic neuropeptide involved in regulating the social behaviour of
all vertebrates, has been proposed as a treatment for a number of neuropsychiatric …

Oxytocin and vasopressin flatten dominance hierarchy and enhance behavioral synchrony in part via anterior cingulate cortex

Y Jiang, ML Platt - Scientific reports, 2018 - nature.com
The neuropeptides oxytocin (OT) and arginine vasopressin (AVP) influence social functions
in many mammals. In humans and rhesus macaques, OT delivered intranasally can promote …

Fear-enhancing effects of septal oxytocin receptors

YF Guzmán, NC Tronson, V Jovasevic, K Sato… - Nature …, 2013 - nature.com
The nonapeptide oxytocin is considered beneficial to mental health due to its anxiolytic,
prosocial and antistress effects, but evidence for anxiogenic actions of oxytocin in humans …

A conditional knockout mouse line of the oxytocin receptor

HJ Lee, HK Caldwell, AH Macbeth, SG Tolu… - …, 2008 - academic.oup.com
Oxytocin plays important roles in reproductive physiology and various behaviors, including
maternal behavior and social memory. Its receptor (Oxtr) is present in peripheral tissues and …

Epigenetic modification of the oxytocin receptor gene influences the perception of anger and fear in the human brain

MH Puglia, TS Lillard, JP Morris… - Proceedings of the …, 2015 - National Acad Sciences
In humans, the neuropeptide oxytocin plays a critical role in social and emotional behavior.
The actions of this molecule are dependent on a protein that acts as its receptor, which is …

Female oxytocin gene‐knockout mice, in a semi‐natural environment, display exaggerated aggressive behavior

AK Ragnauth, N Devidze, V Moy… - Genes, Brain and …, 2005 - Wiley Online Library
Compared to results from a generation of neuropharmacological work, the phenotype of
mice lacking the oxytocin (OT) peptide gene was remarkably normal. An important …

Whole-brain wiring diagram of oxytocin system in adult mice

S Son, SB Manjila, KT Newmaster, Y Wu… - Journal of …, 2022 - Soc Neuroscience
Oxytocin (Oxt) neurons regulate diverse physiological responses via direct connections with
different neural circuits. However, the lack of comprehensive input-output wiring diagrams of …