New aspects of oxytocin receptor function revealed by knockout mice: sociosexual behaviour and control of energy balance
K Nishimori, Y Takayanagi, M Yoshida… - Progress in brain …, 2008 - Elsevier
To further define the function of the oxytocin receptor (OXTR) in vivo, we generated mice
deficient in the Oxtr gene (Oxtr−/−). Oxtr−/− mice had no obvious deficits in fertility or sexual …
deficient in the Oxtr gene (Oxtr−/−). Oxtr−/− mice had no obvious deficits in fertility or sexual …
Oxytocin receptor gene variation predicts empathic concern and autonomic arousal while perceiving harm to others
Recent research indicates that the neuropeptide oxytocin and the gene for the oxytocin
receptor (OXTR) have been implicated in the modulation of various social behaviors …
receptor (OXTR) have been implicated in the modulation of various social behaviors …
Oxytocin enhancement of emotional empathy: generalization across cultures and effects on amygdala activity
Accumulating evidence suggests that the neuropeptide oxytocin (OXT) can enhance
empathy although it is unclear which specific behavioral and neural aspects are influenced …
empathy although it is unclear which specific behavioral and neural aspects are influenced …
Social touch promotes interfemale communication via activation of parvocellular oxytocin neurons
Oxytocin (OT) is a great facilitator of social life but, although its effects on socially relevant
brain regions have been extensively studied, OT neuron activity during actual social …
brain regions have been extensively studied, OT neuron activity during actual social …
Oxytocin increases amygdala reactivity to threatening scenes in females
The neuropeptide oxytocin (OT) is well known for its profound effects on social behavior,
which appear to be mediated by an OT-dependent modulation of amygdala activity in the …
which appear to be mediated by an OT-dependent modulation of amygdala activity in the …
Oxytocin and the neural mechanisms regulating social cognition and affiliative behavior
HE Ross, LJ Young - Frontiers in neuroendocrinology, 2009 - Elsevier
Oxytocin is produced in the hypothalamus and released into the circulation through the
neurohypophyseal system. Peripherally released oxytocin facilitates parturition and milk …
neurohypophyseal system. Peripherally released oxytocin facilitates parturition and milk …
Oxytocin receptor genetic variation relates to empathy and stress reactivity in humans
SM Rodrigues, LR Saslow, N Garcia… - Proceedings of the …, 2009 - National Acad Sciences
Oxytocin, a peptide that functions as both a hormone and neurotransmitter, has broad
influences on social and emotional processing throughout the body and the brain. In this …
influences on social and emotional processing throughout the body and the brain. In this …
Oxytocin and the oxytocin receptor underlie intrastrain, but not interstrain, social recognition
AH Macbeth, HJ Lee, J Edds… - Genes, Brain and …, 2009 - Wiley Online Library
We studied three lines of oxytocin (Oxt) and oxytocin receptor (Oxtr) knockout (KO) male
mice [Oxt−/−, total Oxtr−/− and partial forebrain Oxtr (OxtrFB/FB)] with established deficits in …
mice [Oxt−/−, total Oxtr−/− and partial forebrain Oxtr (OxtrFB/FB)] with established deficits in …
Oxytocin and parental behaviors
The oxytocin/vasopressin ancestor molecule has been regulating reproductive and social
behaviors for more than 500 million years. In all mammals, oxytocin is the hormone …
behaviors for more than 500 million years. In all mammals, oxytocin is the hormone …
Oxytocin and the salience of social cues
BB Averbeck - Proceedings of the National Academy of …, 2010 - National Acad Sciences
The neuropeptide oxytocin (OT) is rapidly moving from a molecule with interesting effects in
model systems to an important mediator of a range of human social behaviors. In this issue …
model systems to an important mediator of a range of human social behaviors. In this issue …