Context: In recent decades, natural products have undisputedly played a leading role in the
development of novel medicines. Yet, trends in the pharmaceutical industry at the level of …

Over the past two decades natural products drug discovery has been increasingly de-
emphasized by pharmaceutical companies. Although heralded on the verge of a comeback …

Nature stands as an inexhaustible source of novel chemotypes and pharmacophores, and
has been a source of medicinal agents for thousands of years, and an impressive number of …

Many natural products have been used as drugs for the treatment of diverse indications.
Although most US pharmaceutical companies have reduced or eliminated their in‐house …

Although traditionally natural products have played an important role in drug discovery, in
the past few years most Big Pharma companies have either terminated or considerably …

Covering: up to March 2013 In addition to their prominent role in basic biological and
chemical research, natural products are a rich source of commercial products for the …

Drug discovery leading to robust and viable lead candidates' remains a challenging
scientific task, which is the transition from a screening hit to a drug candidate, requires …

Historically, most drugs have been derived from natural products, but there has been a shift
away from their use with the increasing predominance of molecular approaches to drug …

Natural products have provided chemical leads for the development of many drugs for
diverse indications. While most US pharmaceutical firms have reduced or eliminated their in …

Natural products and their derivatives have historically been invaluable as a source of
therapeutic agents. However, in the past decade, research into natural products in the …