The specificity of tbe immune response is determined by the interaction between tbe B-cell,
eceptor (BCR) and its cognate structure, antigen. Recent studies have provided …

The subunit structure of the B-cell antigen receptor (BCR) and its associated compart-
mentalization of function confer enormous flexibility for generating signals and directing …

Recent studies have shown that the B-cell antigen receptor (BCR) belongs to the same class
of receptors as the T-cell antigen receptor (TCR) and some of the Fc receptors (FcyRIII …

B lymphocytes use B cell receptors (BCRs) to recognize antigens. It is still not clear how
BCR transduces antigen-specific physical signals upon binding across cell membrane for …

To initiate the humoral immune response, pathogens or foreign substances are recognized
and bound by antigen-specific receptors expressed on the cell surface of mature, resting B …

B‐cell activation is triggered by the binding of antigen to the B‐cell receptor (BCR). The early
molecular events triggered by BCR binding of ligand have been well‐characterized both …

The multimeric nature of the B-cell antigen receptor complex (BCR) was well established at
the time of the 8th International Congress of Immunology in Budapest (reviewed in Refs l-3) …

In B cells, antigen drives the formation of B‐cell receptor (BCR) clusters that initiate the
formation of signaling complexes associated with the cytoplasmic domains of the BCRs …

How the B‐cell antigen receptor (BCR) is activated upon interaction with its cognate antigen
or with anti‐BCR antibodies is not fully understood. We have recently shown that B‐cell …

The B cell antigen receptor (BCR) complex consists of transmembrane (m) Ig, in non-
covalent association with a disulphide-linked heterodimer of mb-1 and B29 gene products …