Disease-associated functions of IL-33: the new kid in the IL-1 family
FY Liew, NI Pitman, IB McInnes - Nature Reviews Immunology, 2010 - nature.com
Abstract Interleukin-33 (IL-33), a newly described member of the IL-1 family, is expressed by
many cell types following pro-inflammatory stimulation and is thought to be released on cell …
many cell types following pro-inflammatory stimulation and is thought to be released on cell …
Interleukin-33 biology with potential insights into human diseases
G Palmer, C Gabay - Nature Reviews Rheumatology, 2011 - nature.com
Abstract Interleukin (IL)-33 is a member of the IL-1 family of cytokines. IL-33 is a nuclear
protein that is also released into the extracellular space, and thus acts as a dual-function …
protein that is also released into the extracellular space, and thus acts as a dual-function …
Targeting IL-33 in autoimmunity and inflammation
TC Theoharides, AI Petra, A Taracanova… - … of Pharmacology and …, 2015 - ASPET
Interleukin-33 (IL-33) belongs to the IL-1 family of cytokines. Whereas IL-1 is processed and
released by live immune cells in response to infection or other triggers, IL-33 is mostly …
released by live immune cells in response to infection or other triggers, IL-33 is mostly …
Interleukin-33 in health and disease
FY Liew, JP Girard, HR Turnquist - Nature Reviews Immunology, 2016 - nature.com
Abstract Interleukin-33 (IL-33)—a member of the IL-1 family—was originally described as an
inducer of type 2 immune responses, activating T helper 2 (TH2) cells and mast cells. Now …
inducer of type 2 immune responses, activating T helper 2 (TH2) cells and mast cells. Now …
Interleukin-33 (IL-33): A critical review of its biology and the mechanisms involved in its release as a potent extracellular cytokine
C Cayrol, JP Girard - Cytokine, 2022 - Elsevier
Abstract Interleukin-33 (IL-33), a member of the IL-1 family, is an alarmin cytokine with
crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic …
crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic …
Role of IL-33 in inflammation and disease
AM Miller - Journal of inflammation, 2011 - Springer
Abstract Interleukin (IL)-33 is a new member of the IL-1 superfamily of cytokines that is
expressed by mainly stromal cells, such as epithelial and endothelial cells, and its …
expressed by mainly stromal cells, such as epithelial and endothelial cells, and its …
The IL-33/ST2 axis: Role in health and disease
Abstract IL-33, an IL-1 family member, is expressed by many cell types and can regulate
gene transcription. IL-33 is released upon cell necrosis and the precursor form is …
gene transcription. IL-33 is released upon cell necrosis and the precursor form is …
IL-33 and IL-33 receptors in host defense and diseases
ABSTRACT Interleukin-33 (IL-33) is a member of the IL-1 cytokine family, which includes IL-
1 and IL-18. IL-33 is considered to be crucial for induction of Th2-type cytokine-associated …
1 and IL-18. IL-33 is considered to be crucial for induction of Th2-type cytokine-associated …
The pleiotropic immunomodulatory functions of IL-33 and its implications in tumor immunity
C Afferni, C Buccione, S Andreone… - Frontiers in …, 2018 - frontiersin.org
Interleukin-33 (IL-33) is a IL-1 family member of cytokines exerting pleiotropic activities. In
the steady-state, IL-33 is expressed in the nucleus of epithelial, endothelial, and fibroblast …
the steady-state, IL-33 is expressed in the nucleus of epithelial, endothelial, and fibroblast …
New dog and new tricks: evolving roles for IL-33 in type 2 immunity
JM Lott, TL Sumpter, HR Turnquist - Journal of Leucocyte …, 2015 - academic.oup.com
IL-33 is a more recently identified member of the IL-1 cytokine family, expressed in the
nucleus of epithelial cells and released into the extracellular space following tissue damage …
nucleus of epithelial cells and released into the extracellular space following tissue damage …