IL-33 is a chromatin-associated cytokine of the IL-1 family that has recently been linked to
many diseases, including asthma, rheumatoid arthritis, atherosclerosis, and cardiovascular …

Interleukin (IL)-33 belongs to IL-1 cytokine family which is constitutively produced from the
structural and lining cells including fibroblasts, endothelial cells, and epithelial cells of skin …

Interleukin 33 (IL-33) is an alarmin cytokine from the IL-1 family. IL-33 is localized in the
nucleus and acts there as a gene regulator. Following injury, stress or cell death, it is …

Abstract IL-33 is an IL-1-related cytokine which has been implicated in Th2-associated
biology and allergic diseases in humans and mice. IL-33 stimulates Th2 cells, mast cells …

The discovery of IL-33 as the ligand for the orphan Th2 associated receptor ST2 has
uncovered a whole range of different avenues for this pathway. Although the extracellular …

Abstract IL-33 is an IL-1 family member recently identified as the ligand for T1/ST2 (ST2), a
member of the IL-1 receptor family. ST2 is stably expressed on mast cells and Th2 effector T …

In complex disorders such as asthma and allergic disease, the goal for developing disease-
modifying biotherapeutics is to find a target that is a central instigator of immunologic activity …

Abstract Interleukin (IL)-33 signals influence various immune cells during differentiation,
immune responses and homeostasis. As discussed in this Review, IL-33 via TI/ST2L …

Interleukin (IL)-33 is a member of the IL-1 cytokine family that has been shown to play an
important role in the induction and effector phases of type 2 immune responses. Both innate …

Allergic diseases, which include asthma, allergic rhinitis (AR), chronic rhinosinusitis (CRS),
atopic dermatitis (AD), food allergy (FA), allergic keratoconjunctivitis, seriously affect the …