Many lines of independent research have provided convergent evidence regarding
oxidative stress, cerebrovascular disease, dementia, and Alzheimer's disease (AD). Clinical …

Alzheimer's disease (AD) and stroke are two leading causes of age‐associated dementia. A
rapidly growing body of evidence indicates that increased oxidative stress from reactive …

Oxidative stress is a key factor involved in the development and progression of Alzheimer's
disease, and it is well documented that free radical oxidative damage, particularly of …

Over the past decade, the study of oxidative stress in relation to the pathogenesis of
Alzheimer's and other neurodegenerative diseases has been transformed from an esoteric …

Purpose: Since the description of his original patient Auguste D. with cognitive disability,
Alois Alzheimer persisted in his clinical investigations to understand this complex disease …

Age has a powerful effect on enhanced susceptibility to neurodegenerative diseases,
including susceptibility to stroke and cognitive impairment (CI) even in optimally healthy …

Several factors have been implicated in Alzheimer's disease (AD) but there is no definite
conclusion as to the main pathogenic agents. Mutations in the amyloid precursor protein …

Alzheimer's disease (AD) is a highly disabling progressive neurodegenerative disorder
characterized by a steadily growing number of patients, by the absence of a cure for the …

Alzheimer's disease (AD) is slowly but steadily undergoing a profound reshaping of the
definition and approach caused by the frustrating gap between poorly controlled AD …

Oxidative stress, an overproduction of free radicals or a diminution of free radical
scavenging ability relative to those of cognitively aged-matched controls, is widely …