Rosmarinic acid protects mice from lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting MAPKs/NF-κB and activating Nrf2/HO-1 signaling …

Z Li, H Feng, Y Wang, B Shen, Y Tian, L Wu… - International …, 2019 - Elsevier
Rosmarinic acid (RA) has antioxidation, anticancer, antibacterial, anti-inflammatory and
various biological functions. In our study, we aim to evaluate effects of RA on acute liver …

Neuroprotective effect of wogonin: potential roles of inflammatory cytokines

HZ Piao, SA Jin, HS Chun, JC Lee, WK Kim - Archives of pharmacal …, 2004 - Springer
Abstract Wogonin (5, 7-dihydroxy-8-methoxyflavone), an active component originated from
the root of Scutellaria baicalensis Georgi, has been reported to possess antioxidant and anti …

Emodin ameliorated lipopolysaccharide-induced fulminant hepatic failure by blockade of TLR4/MD2 complex expression in D-galactosamine-sensitized mice

X Yin, X Gong, R Jiang, G Kuang, B Wang… - International …, 2014 - Elsevier
Emodin has been reported to possess anti-inflammatory and anti-oxidant activities. The aim
of this study was to explore the effect and mechanism of emodin on lipopolysaccharide …

CQMUH-011, a novel adamantane sulfonamide compound, inhibits lipopolysaccharide-and D-galactosamine-induced fulminant hepatic failure in mice

L Yan, X Hu, Q Wu, R Jiang, S Zhang, Q Ling… - International …, 2017 - Elsevier
CQMUH-011, a novel adamantane sulfonamide compound, was shown to suppress
macrophage activation and proliferation in our previous study. However, it is unknown …

Hepatoprotective effects of vicenin-2 and scolymoside through the modulation of inflammatory pathways

IC Lee, JS Bae - Journal of natural medicines, 2020 - Springer
The aim of this study was to investigate the effects of two structurally related flavonoids found
in Cyclopia subternata, vicenin-2 (VCN) and scolymoside (SCL) on lipopolysaccharide …

[HTML][HTML] Amygdalin attenuates acute liver injury induced by D-galactosamine and lipopolysaccharide by regulating the NLRP3, NF-κB and Nrf2/NQO1 signalling …

F Tang, K Fan, K Wang, C Bian - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Acute liver injury (ALI) is a life-threatening syndrome accompanied by overwhelming
inflammation. Amygdalin (AGD) has been reported to possess various biological activities …

Genipin protects d-galactosamine and lipopolysaccharide-induced hepatic injury through suppression of the necroptosis-mediated inflammasome signaling

MJ Seo, JM Hong, SJ Kim, SM Lee - European journal of pharmacology, 2017 - Elsevier
Acute liver failure (ALF) is a life-threatening syndrome resulting from massive inflammation
and hepatocyte death. Necroptosis, a programmed cell death controlled by receptor …

Costunolide protects lipopolysaccharide/d-galactosamine–induced acute liver injury in mice by inhibiting NF-κB signaling pathway

Y Wang, X Zhang, L Zhao, M Shi, Z Wei, Z Yang… - Journal of Surgical …, 2017 - Elsevier
Background Costunolide, a well-known sesquiterpene lactone, has been reported to have
anti-inflammatory and anti-oxidative effects. Methods In this study, we aim to investigate the …

Luzindole attenuates LPS/d-galactosamine-induced acute hepatitis in mice

Y Luo, Y Yang, Y Shen, L Li, J Huang… - Innate …, 2020 - journals.sagepub.com
Melatonin is a well-documented hormone that plays central roles in the regulation of sleep–
wake cycles. There is cumulative evidence to suggest that melatonin is also a pleiotropic …

The protective effects of total saponins from Ornithogalum saundersiae (Liliaceae) on acute hepatic failure induced by lipopolysaccharide and D-galactosamine in …

YL Wu, XC Feng, LH Lian, YZ Jiang, JX Nan - Journal of …, 2010 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: This study examined the protective effects of
total saponins from Ornithogalum saundersiae (Liliaceae) on d-galactosamine (d-GalN) and …